MAGEA2B and TNIP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAGEA2B	TNIP3
Description		MAGE family member A2B	TNFAIP3 interacting protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus PML Body	Cytoplasm Cytosol
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding DNA-binding Transcription Factor Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Catabolic Process Negative Regulation Of Protein Sumoylation Positive Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction By P53 Class Mediator Cellular Senescence Negative Regulation Of Protein Acetylation	MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Transcription By RNA Polymerase II Inflammatory Response Toll-like Receptor 4 Signaling Pathway Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Canonical NF-kappaB Signal Transduction Cellular Response To Lipopolysaccharide
Pathways			Ovarian tumor domain proteases
Drugs
Diseases
GWAS			Breast cancer ( 23468962) Multiple sclerosis ( 31604244)
Interacting Genes		24 interacting genes: ACSM1 ANKRD45 BEX1 BEX2 CCDC185 CEP57 CEP57L1 COQ4 COX7C DYNLRB1 KRT8P12 MBD3 NTAQ1 P4HA3 PHKG2 POLL PSMC1 SEPTIN5 SMARCD1 TNIP3 TRIM28 TRIM31 TUBB ZNF655	25 interacting genes: CCN3 CYSRT1 DAZAP2 FAM161A KPNA3 KRT40 KRTAP10-3 KRTAP10-8 LITAF LZTS2 MAGEA2 MAGEA2B MTUS2 NBPF19 NOTCH2NLA NTAQ1 PIBF1 PLSCR3 TAX1BP1 TCEANC TNIP1 TRIM55 TRIM63 UBC ZBTB8A
Entrez ID		266740	79931
HPRD ID		14347	16268
Ensembl ID		ENSG00000183305	ENSG00000050730
Uniprot IDs		P43356	Q96KP6
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Protein Acetylation Negative Regulation Of Protein Sumoylation Positive Regulation Of Ubiquitin-protein Transferase Activity
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