SPATA24 and EHD2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		SPATA24	EHD2
Description		spermatogenesis associated 24	EH domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol	Nucleus Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Caveola Endosome Membrane Membrane Endocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	Nucleotide Binding Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Spermatogenesis Cell Differentiation	Endocytosis Cortical Actin Cytoskeleton Organization Endocytic Recycling Cilium Assembly Protein Localization To Plasma Membrane Plasma Membrane Tubulation Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Malaria ( 31844061)
Interacting Genes		24 interacting genes: CALCOCO2 CAMK2D CEP72 CTNNBIP1 CYSRT1 EFEMP2 EHD2 FLOT2 KDM1A KRT31 KRT40 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP4-2 LZTS2 MDFI MID2 NBPF19 NOTCH2NLA OIP5 PLEKHF2 PTAFR SUV39H1	14 interacting genes: AP1M1 AP1M2 AP2M1 BPGM CDC42 DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23
Entrez ID		202051	30846
HPRD ID		19510	10434
Ensembl ID		ENSG00000170469	ENSG00000024422
Uniprot IDs		Q86W54	Q9NZN4
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Identical Protein Binding	Cytosol Intracellular Transport Clathrin Adaptor Complex Cellular Localization Establishment Of Localization In Cell Clathrin Adaptor Activity Clathrin-coated Vesicle Vesicle-mediated Transport Extrinsic Component Of Presynaptic Endocytic Zone Membrane Protein Transport Intracellular Protein Localization Clathrin-coated Pit Establishment Of Protein Localization AP-1 Adaptor Complex Intracellular Protein Transport Regulation Of Endocytosis Regulation Of Vesicle Size Trans-Golgi Network Membrane Regulation Of Receptor-mediated Endocytosis Clathrin-coated Endocytic Vesicle Synaptic Vesicle Low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Receptor Internalization Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Endocytosis Clathrin-dependent Endocytosis Dendritic Spine Organization Vesicle Budding From Membrane Cytoplasmic Vesicle Membrane Endocytosis Clathrin-coated Vesicle Membrane Vesicle Cytoplasmic Vesicle Extracellular Exosome Neuron Projection Organization Postsynapse Organization Regulation Of Vesicle-mediated Transport Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Positive Regulation Of Receptor-mediated Endocytosis Endosomal Transport Import Into Cell Membrane Organization Receptor Internalization GBD Domain Binding Storage Vacuole Endocytic Vesicle Membrane Positive Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway Regulation Of Receptor Internalization
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