SPATA24 and EHD2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SPATA24	EHD2
Gene Name		spermatogenesis associated 24	EH-domain containing 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm	Nucleus Plasma Membrane Caveola Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Protein Homodimerization Activity	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development Spermatogenesis Cell Differentiation	Endocytosis Blood Coagulation Metabolic Process Cortical Actin Cytoskeleton Organization Endocytic Recycling Protein Localization To Plasma Membrane Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: CALCOCO2 CAMK2D CEP72 EHD2 FLOT2 KDM1A KRT31 KRT40 KRTAP4-2 LZTS2 MID2 PTAFR SUV39H1	13 interactors: AP1M1 AP1M2 AP2M1 BPGM DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23
Entrez ID		202051	30846
HPRD ID		19510	10434
Ensembl ID		ENSG00000170469	ENSG00000024422
Uniprot IDs		Q86W54	Q9NZN4
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Interferon-gamma Response To Stress Innate Immune Response Regulation Of Primitive Erythrocyte Differentiation Establishment Of Protein Localization To Plasma Membrane Gamma-tubulin Complex Localization Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Interferon-gamma-mediated Signaling Pathway Regulation Of Histone Modification Spindle Organization Immune System Process Regulation Of Generation Of L-type Calcium Current Inositol Trisphosphate Biosynthetic Process Cellular Response To Interferon-gamma Immune Response Protein Localization To Plasma Membrane Positive Regulation Of Rac Protein Signal Transduction Regulation Of Histone Deacetylase Activity Negative Regulation Of Gene Expression Defense Response Cellular Protein Localization Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Muscle Cell Development Cellular Localization Histone H3-K9 Dimethylation Negative Regulation Of Sodium Ion Transmembrane Transport Inositol Phosphate Biosynthetic Process Regulation Of Relaxation Of Cardiac Muscle Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Regulation Of Cardiac Muscle Cell Action Potential Histone H3-K4 Demethylation Protein Localization To Microtubule Response To Cytokine Positive Regulation Of Endocytic Recycling Inositol Trisphosphate Metabolic Process Regulation Of Relaxation Of Muscle Cellular Potassium Ion Homeostasis Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of Chromosome Organization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Growth Involved In Cardiac Muscle Cell Development Plasma Membrane Organization Positive Regulation Of Megakaryocyte Differentiation Regulation Of Endocytic Recycling Spindle Midzone Assembly Establishment Of Protein Localization To Membrane Histone H3-K9 Trimethylation	Regulation Of Defense Response To Virus By Virus Membrane Organization Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Cell Differentiation Clathrin-mediated Endocytosis Antigen Processing And Presentation Of Peptide Antigen Golgi Vesicle Transport Vesicle-mediated Transport Antigen Processing And Presentation Intracellular Transport Amylopectin Biosynthetic Process Positive Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Intracellular Protein Transport Developmental Process Post-Golgi Vesicle-mediated Transport Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Establishment Of Localization In Cell Viral Process Immune System Process Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Synaptic Transmission Cellular Protein Localization Cargo Loading Into Vesicle Protein Transport Cellular Localization Iron Ion Import Into Cell Establishment Of Protein Localization Regulation Of Endocytosis DNA Methylation Involved In Embryo Development Establishment Of Vesicle Localization Vesicle Organization Pigment Granule Maturation Endosome To Melanosome Transport Glucose Import Endosomal Transport Vesicle Localization Dendritic Spine Maintenance Cellular Pigment Accumulation Synaptic Vesicle Maturation Positive Regulation Of Beta-amyloid Formation Neuronal Ion Channel Clustering Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Iron Ion Import Negative Regulation Of Actin Nucleation
Tagcloud ?			acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 enrichment fhl2 homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly
Tagcloud (Difference) ?			acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 enrichment fhl2 homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly
Tagcloud (Intersection) ?