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SPATA24 and CAMK2D
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
SPATA24
CAMK2D
Gene Name
spermatogenesis associated 24
calcium/calmodulin-dependent protein kinase II delta
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Endocytic Vesicle Membrane
Sarcoplasmic Reticulum Membrane
Calcium Channel Complex
Sarcolemma
Perinuclear Region Of Cytoplasm
Molecular Function
DNA Binding
Protein Homodimerization Activity
Protein Serine/threonine Kinase Activity
Calmodulin-dependent Protein Kinase Activity
Protein Binding
Calmodulin Binding
ATP Binding
Sodium Channel Inhibitor Activity
Titin Binding
Protein Homodimerization Activity
Ion Channel Binding
Nitric-oxide Synthase Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Multicellular Organismal Development
Spermatogenesis
Cell Differentiation
Regulation Of Cell Growth
Response To Hypoxia
Regulation Of The Force Of Heart Contraction
Regulation Of Membrane Depolarization
Regulation Of Transcription From RNA Polymerase II Promoter
Protein Phosphorylation
Synaptic Transmission
Regulation Of Heart Contraction
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Cardiac Muscle Hypertrophy
Regulation Of Cell Communication By Electrical Coupling
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Positive Regulation Of Smooth Muscle Cell Migration
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Cytokine-mediated Signaling Pathway
Cellular Potassium Ion Homeostasis
Endoplasmic Reticulum Calcium Ion Homeostasis
Cellular Response To Heat
Positive Regulation Of Rac Protein Signal Transduction
Protein Autophosphorylation
Positive Regulation Of Smooth Muscle Cell Proliferation
Protein Oligomerization
Relaxation Of Cardiac Muscle
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Interferon-gamma-mediated Signaling Pathway
Regulation Of Cellular Localization
Cell Growth Involved In Cardiac Muscle Cell Development
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Calcium Ion
Cardiac Muscle Cell Contraction
Regulation Of Heart Rate By Cardiac Conduction
Regulation Of Cardiac Muscle Cell Action Potential
Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction
Regulation Of Cellular Response To Heat
Regulation Of Histone Deacetylase Activity
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Regulation Of Relaxation Of Cardiac Muscle
Negative Regulation Of Sodium Ion Transmembrane Transport
Regulation Of Generation Of L-type Calcium Current
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways
Interferon Signaling
Cytokine Signaling in Immune system
Cellular response to heat stress
CREB phosphorylation through the activation of Ras
Trafficking of AMPA receptors
Interferon gamma signaling
HSF1-dependent transactivation
Activation of NMDA receptor upon glutamate binding and postsynaptic events
CREB phosphorylation through the activation of CaMKII
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
Unblocking of NMDA receptor, glutamate binding and activation
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Ras activation uopn Ca2+ infux through NMDA receptor
Post NMDA receptor activation events
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
White matter integrity (interaction) (
23218918
)
Protein-Protein Interactions
13 interactors:
CALCOCO2
CAMK2D
CEP72
EHD2
FLOT2
KDM1A
KRT31
KRT40
KRTAP4-2
LZTS2
MID2
PTAFR
SUV39H1
27 interactors:
ACTN2
ARL2BP
BANP
CAMK2B
CD5
CREM
DNAL4
EPHA10
FAM171B
FKBP1B
FNDC3B
FXR2
GRIN2B
HDAC4
HNMT
IFNGR2
MOAP1
MRPL11
RPS18
RPS4X
SPATA24
SRPK1
STAT1
TNPO2
TTC5
VIM
WASF3
Entrez ID
202051
817
HPRD ID
19510
09653
Ensembl ID
ENSG00000170469
ENSG00000145349
Uniprot IDs
Q86W54
D6R938
E9PF82
Q13557
PDB IDs
2VN9
2W2C
2WEL
3GP2
Enriched GO Terms of Interacting Partners
?
Response To Interferon-gamma
Response To Stress
Innate Immune Response
Regulation Of Primitive Erythrocyte Differentiation
Establishment Of Protein Localization To Plasma Membrane
Gamma-tubulin Complex Localization
Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction
Cardiac Muscle Cell Contraction
Interferon-gamma-mediated Signaling Pathway
Regulation Of Histone Modification
Spindle Organization
Immune System Process
Regulation Of Generation Of L-type Calcium Current
Inositol Trisphosphate Biosynthetic Process
Cellular Response To Interferon-gamma
Immune Response
Protein Localization To Plasma Membrane
Positive Regulation Of Rac Protein Signal Transduction
Regulation Of Histone Deacetylase Activity
Negative Regulation Of Gene Expression
Defense Response
Cellular Protein Localization
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Muscle Cell Development
Cellular Localization
Histone H3-K9 Dimethylation
Negative Regulation Of Sodium Ion Transmembrane Transport
Inositol Phosphate Biosynthetic Process
Regulation Of Relaxation Of Cardiac Muscle
Negative Regulation Of Histone H3-K4 Methylation
Histone H3-K9 Demethylation
Regulation Of Cardiac Muscle Cell Action Potential
Histone H3-K4 Demethylation
Protein Localization To Microtubule
Response To Cytokine
Positive Regulation Of Endocytic Recycling
Inositol Trisphosphate Metabolic Process
Regulation Of Relaxation Of Muscle
Cellular Potassium Ion Homeostasis
Regulation Of Cardiac Muscle Cell Membrane Potential
Regulation Of Chromosome Organization
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cell Growth Involved In Cardiac Muscle Cell Development
Plasma Membrane Organization
Positive Regulation Of Megakaryocyte Differentiation
Regulation Of Endocytic Recycling
Spindle Midzone Assembly
Establishment Of Protein Localization To Membrane
Histone H3-K9 Trimethylation
Signaling
Cell Communication
Muscle System Process
Protein Localization To Organelle
Signal Transduction
Viral Process
Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling
Regulation Of Interferon-gamma-mediated Signaling Pathway
Regulation Of Response To Interferon-gamma
Cell Differentiation
Interferon-gamma-mediated Signaling Pathway
Multicellular Organismal Development
Response To Stress
Developmental Process
Regulation Of Cellular Process
Translational Termination
Cellular Response To Interferon-gamma
Actin-myosin Filament Sliding
Muscle Filament Sliding
Response To Stimulus
Response To Organic Substance
Cellular Response To Stimulus
Response To Cytokine
Response To Interferon-gamma
Translational Elongation
Negative Regulation Of Transporter Activity
Cellular Protein Complex Disassembly
Actin-mediated Cell Contraction
Negative Regulation Of Macrophage Fusion
Inhibitory G-protein Coupled Receptor Phosphorylation
Negative Regulation Of Ion Transmembrane Transport
Protein Complex Disassembly
Gene Expression
Muscle Contraction
Negative Regulation Of Transmembrane Transport
Regulation Of Cell Development
Nervous System Development
Establishment Of Protein Localization To Membrane
Translational Initiation
Enzyme Linked Receptor Protein Signaling Pathway
Defense Response
Actin Filament-based Movement
Cellular Protein Localization
Cellular Localization
Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation
Activation Of Meiosis Involved In Egg Activation
Negative Regulation By Virus Of Viral Protein Levels In Host Cell
Positive Regulation Of Sequestering Of Calcium Ion
Protein Localization
Regulation Of Cardiac Muscle Contraction
Tagcloud
?
abcc8
acacb
cacna1a
cdkal1
chi
csmd1
disequilibrium
exome
glud1
gnas
hnf1a
hyperinsulinism
kcnh6
kcnj10
kcnj11
nos2
notch2
pde4c
pik3r3
probands
ryr3
scn8a
slc24a6
slc37a3
sulf1
tdt
tll1
trpc5
trpv3
Tagcloud (Difference)
?
abcc8
acacb
cacna1a
cdkal1
chi
csmd1
disequilibrium
exome
glud1
gnas
hnf1a
hyperinsulinism
kcnh6
kcnj10
kcnj11
nos2
notch2
pde4c
pik3r3
probands
ryr3
scn8a
slc24a6
slc37a3
sulf1
tdt
tll1
trpc5
trpv3
Tagcloud (Intersection)
?