EMD and NPDC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EMD	NPDC1
Description		emerin	neural proliferation, differentiation and control 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Spindle Cytosol Microtubule Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum TMEM240-body	Plasma Membrane Membrane
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Beta-tubulin Binding	Protein Binding
	Biological Process	Muscle Contraction Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Nuclear Membrane Organization Negative Regulation Of Canonical Wnt Signaling Pathway Amyloid Fibril Formation
Pathways		Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerization of the Nuclear Lamina RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases		Emery-Dreifuss muscular dystrophy
GWAS		Mean spheric corpuscular volume ( 32888494)	Lymphocyte count ( 27863252) Monocyte percentage of white cells ( 27863252 32888494) White blood cell count ( 27863252 32888494)
Interacting Genes		100 interacting genes: ABL1 ABT1 ACTB ACTG2 AEN AKAP8L ANK1 ANKS6 AQP6 AVPI1 BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CCNL2 CD33 CEP70 CERS4 CISD2 CLEC14A COMT COPS6 CPLX4 CREB3 CTNNBIP1 CXorf66 DPPA4 EFHC2 ERMAP FAM209A FATE1 GMCL1 GOLM2 GORAB GPR152 GRAMD2A HSF2BP INCA1 KASH5 KCNJ12 KCNJ18 KCNJ8 KCNN3 KIF9 KIR2DL3 LIME1 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 MEOX1 MEOX2 MMGT1 MRPL45 MTERF4 MTNR1A NCAPH2 NF2 NPDC1 PAK5 PIMREG PSME1 REL RNASEH1 RNF123 SH3GL2 SH3GL3 SLC10A1 SLC35H1 SOWAHB SRC SSMEM1 STX1A SYNE1 TCF23 TMEM174 TMEM200A TMEM201 TMEM52B TMEM80 TMX2 TRAF3IP3 TRIM42 VAV1 WEE2-AS1 YTHDC1 ZFP1 ZFP57 ZFP64 ZNF165 ZNF232 ZNF329 ZNF341 ZNF398 ZNF549 ZNF774	41 interacting genes: C3orf52 CCND1 CCND2 CCND3 CDK2 CPT1A CYSRT1 E2F1 EMD FHL5 HINFP HNRNPK KHDRBS2 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-1 KRTAP4-12 KRTAP4-4 KRTAP5-9 KRTAP9-3 MADD MAL MDFI MS4A13 NBPF19 NOTCH2NLA PLSCR1 RBMY1F RBMY1J TFDP1
Entrez ID		2010	56654
HPRD ID		02309	12048
Ensembl ID		ENSG00000102119	ENSG00000107281
Uniprot IDs		P50402	Q9NQX5
PDB IDs		1JEI 2ODC 2ODG 6GHD 6RPR 7NDY
Enriched GO Terms of Interacting Partners?		Protein Binding Inward Rectifier Potassium Channel Activity Fc-gamma Receptor Signaling Pathway	Intermediate Filament Keratin Filament Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Cyclin-dependent Protein Kinase Holoenzyme Complex Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G1/S Phase Transition Cytosol Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Negative Regulation Of Fat Cell Proliferation Rb-E2F Complex Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition DNA Damage Checkpoint Signaling Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Regulation Of MRNA Processing Anoikis Positive Regulation Of Cell Cycle Process Signal Transduction In Response To DNA Damage Hair Cycle Protein Serine/threonine Kinase Activator Activity Identical Protein Binding Mitotic G1 DNA Damage Checkpoint Signaling Mitotic G1/S Transition Checkpoint Signaling Regulation Of Cell Cycle Regulation Of RNA Splicing Positive Regulation Of Cell Cycle Regulation Of MRNA Metabolic Process Regulation Of Mitotic Cell Cycle Microtubule Organizing Center Response To X-ray Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Cell Cycle Phase Transition Liver Regeneration TMEM240-body Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane
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