EMD and MTERF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EMD	MTERF4
Description		emerin	mitochondrial transcription termination factor 4
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Spindle Cytosol Microtubule Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum TMEM240-body	Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Beta-tubulin Binding	Nucleic Acid Binding RNA Binding Protein Binding RRNA Binding
	Biological Process	Muscle Contraction Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Nuclear Membrane Organization Negative Regulation Of Canonical Wnt Signaling Pathway Amyloid Fibril Formation	RRNA Processing Mitochondrial Transcription Protein Targeting To Mitochondrion Heart Development Ribosome Assembly Camera-type Eye Development Mitochondrial Ribosome Assembly Regulation Of Mitochondrial Transcription
Pathways		Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerization of the Nuclear Lamina RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	rRNA modification in the mitochondrion
Drugs
Diseases		Emery-Dreifuss muscular dystrophy
GWAS		Mean spheric corpuscular volume ( 32888494)
Interacting Genes		100 interacting genes: ABL1 ABT1 ACTB ACTG2 AEN AKAP8L ANK1 ANKS6 AQP6 AVPI1 BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CCNL2 CD33 CEP70 CERS4 CISD2 CLEC14A COMT COPS6 CPLX4 CREB3 CTNNBIP1 CXorf66 DPPA4 EFHC2 ERMAP FAM209A FATE1 GMCL1 GOLM2 GORAB GPR152 GRAMD2A HSF2BP INCA1 KASH5 KCNJ12 KCNJ18 KCNJ8 KCNN3 KIF9 KIR2DL3 LIME1 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 MEOX1 MEOX2 MMGT1 MRPL45 MTERF4 MTNR1A NCAPH2 NF2 NPDC1 PAK5 PIMREG PSME1 REL RNASEH1 RNF123 SH3GL2 SH3GL3 SLC10A1 SLC35H1 SOWAHB SRC SSMEM1 STX1A SYNE1 TCF23 TMEM174 TMEM200A TMEM201 TMEM52B TMEM80 TMX2 TRAF3IP3 TRIM42 VAV1 WEE2-AS1 YTHDC1 ZFP1 ZFP57 ZFP64 ZNF165 ZNF232 ZNF329 ZNF341 ZNF398 ZNF549 ZNF774	11 interacting genes: APP ATXN1 BANP CIDEB CRYAA DGAT2L6 EMD FOS OSGIN1 TNFRSF10D UBC
Entrez ID		2010	130916
HPRD ID		02309	14699
Ensembl ID		ENSG00000102119	ENSG00000122085
Uniprot IDs		P50402	B4DFP7 Q7Z6M4
PDB IDs		1JEI 2ODC 2ODG 6GHD 6RPR 7NDY	4FP9 4FZV 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF3 7OF5 7OF7 7OIC 7PD3 8PK0 8QSJ
Enriched GO Terms of Interacting Partners?		Protein Binding Inward Rectifier Potassium Channel Activity Fc-gamma Receptor Signaling Pathway	Response To Light Stimulus Associative Learning Memory Learning Response To Radiation Amyloid Fibril Formation Amyloid-beta Complex Growth Cone Lamellipodium Visual Behavior Regulation Of Response To Calcium Ion Learning Or Memory Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To Growth Factor Stimulus Visual Learning Identical Protein Binding TMEM240-body Skeletal Muscle Cell Differentiation Medium-term Memory Cellular Response To Prolactin Acetylcholine Receptor Activator Activity PTB Domain Binding Apoptotic Process Cognition Adult Locomotory Behavior Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Response To Growth Factor Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle System Process Endoplasmic Reticulum Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Nervous System Process Response To Prolactin Conditioned Taste Aversion Acylglycerol Acyl-chain Remodeling Programmed Cell Death Cell Death Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus
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