EMD and CXorf66

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EMD	CXorf66
Description		emerin	chromosome X open reading frame 66
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Spindle Cytosol Microtubule Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum TMEM240-body	Membrane
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Beta-tubulin Binding	Protein Binding
	Biological Process	Muscle Contraction Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Nuclear Membrane Organization Negative Regulation Of Canonical Wnt Signaling Pathway Amyloid Fibril Formation
Pathways		Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerization of the Nuclear Lamina RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases		Emery-Dreifuss muscular dystrophy
GWAS		Mean spheric corpuscular volume ( 32888494)
Interacting Genes		100 interacting genes: ABL1 ABT1 ACTB ACTG2 AEN AKAP8L ANK1 ANKS6 AQP6 AVPI1 BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CCNL2 CD33 CEP70 CERS4 CISD2 CLEC14A COMT COPS6 CPLX4 CREB3 CTNNBIP1 CXorf66 DPPA4 EFHC2 ERMAP FAM209A FATE1 GMCL1 GOLM2 GORAB GPR152 GRAMD2A HSF2BP INCA1 KASH5 KCNJ12 KCNJ18 KCNJ8 KCNN3 KIF9 KIR2DL3 LIME1 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 MEOX1 MEOX2 MMGT1 MRPL45 MTERF4 MTNR1A NCAPH2 NF2 NPDC1 PAK5 PIMREG PSME1 REL RNASEH1 RNF123 SH3GL2 SH3GL3 SLC10A1 SLC35H1 SOWAHB SRC SSMEM1 STX1A SYNE1 TCF23 TMEM174 TMEM200A TMEM201 TMEM52B TMEM80 TMX2 TRAF3IP3 TRIM42 VAV1 WEE2-AS1 YTHDC1 ZFP1 ZFP57 ZFP64 ZNF165 ZNF232 ZNF329 ZNF341 ZNF398 ZNF549 ZNF774	12 interacting genes: AQP6 ASPH EMD ERGIC3 LAT POMGNT1 RPRM RTP2 STX10 TMEM31 TMX2 YIPF6
Entrez ID		2010	347487
HPRD ID		02309	18139
Ensembl ID		ENSG00000102119	ENSG00000203933
Uniprot IDs		P50402	Q5JRM2
PDB IDs		1JEI 2ODC 2ODG 6GHD 6RPR 7NDY
Enriched GO Terms of Interacting Partners?		Protein Binding Inward Rectifier Potassium Channel Activity Fc-gamma Receptor Signaling Pathway	Membrane Cortical Endoplasmic Reticulum Positive Regulation Of Intracellular Protein Transport Regulation Of Intracellular Protein Transport Positive Regulation Of Intracellular Transport COPII-coated ER To Golgi Transport Vesicle PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Peptidyl-aspartic Acid 3-dioxygenase Activity Regulation Of Intracellular Transport Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Transport TMEM240-body Golgi Membrane Golgi Apparatus Golgi Vesicle Transport TCR Signalosome Retrograde Transporter Complex, Golgi To ER Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,3-N-acetylglucosaminyltransferase Activity Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Endoplasmic Reticulum Detection Of Chemical Stimulus Regulation Of Protein Localization Cellular Localization Transporter Complex Olfactory Receptor Binding Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Activation Of Store-operated Calcium Channel Activity Positive Regulation Of Protein Localization Regulation Of Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Localization Of Cell Positive Regulation Of Store-operated Calcium Channel Activity Reactive Gliosis
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