EMD and CREB3

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EMD	CREB3
Gene Name		emerin	cAMP responsive element binding protein 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Microtubule Membrane Integral Component Of Membrane Nuclear Membrane	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Integral Component Of Membrane Nuclear Body Integral Component Of Endoplasmic Reticulum Membrane Neuronal Cell Body
	Molecular Function	Actin Binding Protein Binding Beta-tubulin Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding CAMP Response Element Binding Protein Binding CCR1 Chemokine Receptor Binding CAMP Response Element Binding Protein Homodimerization Activity Protein Dimerization Activity
	Biological Process	Mitotic Cell Cycle Muscle Contraction Mitotic Nuclear Envelope Disassembly Mitotic Nuclear Envelope Reassembly Muscle Organ Development Negative Regulation Of Catenin Import Into Nucleus Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus	Regulation Of Cell Growth Positive Regulation Of Defense Response To Virus By Host Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Chemotaxis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Viral Process Establishment Of Viral Latency Release From Viral Latency Positive Regulation Of Cell Migration Response To Endoplasmic Reticulum Stress Regulation Of Cell Proliferation Cytoplasmic Sequestering Of Transcription Factor Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Induction Of Positive Chemotaxis Positive Regulation Of Calcium Ion Transport Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Deacetylase Activity Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Pathways		Mitotic Prophase Nuclear Envelope Breakdown Depolymerisation of the Nuclear Lamina Nuclear Envelope Reassembly Clearance of Nuclear Envelope Membranes from Chromatin Mitotic Anaphase Initiation of Nuclear Envelope Reformation Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: ABT1 ACTB ACTG2 AEN AKAP8L BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CEP70 COPS6 CREB3 CTNNBIP1 DPPA4 EFHC2 FATE1 GMCL1 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 PAK7 PSME1 SH3GL2 SH3GL3 SYNE1 TRAF3IP3 TRIM42 VAV1 YTHDC1 ZNF165 ZNF232	25 interactors: APPBP2 ATF3 ATF4 BCAT2 BNIP2 CCR1 CEBPG CLP1 CREB3L1 CREB3L3 DDIT3 EMD HCFC1 HDAC3 JUN MALL NFE2L2 NFE2L3 NFIL3 OS9 RABAC1 RRAS2 SQLE STX8 TTLL5
Entrez ID		2010	10488
HPRD ID		02309	07339
Ensembl ID		ENSG00000102119	ENSG00000107175
Uniprot IDs		P50402	O43889
PDB IDs		1JEI 2ODC 2ODG
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Envelope Reassembly Establishment Of Viral Latency Nuclear Envelope Reassembly Regulation Of DNA-templated Transcription, Initiation Nucleus Organization Apoptotic Process Mitotic Nuclear Envelope Disassembly Programmed Cell Death Cell Death Death Nuclear Envelope Disassembly Negative Regulation Of Signal Transduction Sterol Regulatory Element Binding Protein Import Into Nucleus Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity	Response To Endoplasmic Reticulum Stress Transcription From RNA Polymerase II Promoter Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Positive Regulation Of Gene Expression Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription, DNA-templated Regulation Of DNA-templated Transcription In Response To Stress RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Cellular Response To Stress Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Cellular Nitrogen Compound Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nuclease Activity Regulation Of Phosphorylation Circadian Rhythm Negative Regulation Of Biosynthetic Process Positive Regulation Of Neuron Apoptotic Process Response To Stress Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Regulation Of Gene Expression Positive Regulation Of Neuron Death Regulation Of Phosphorus Metabolic Process
Tagcloud ?		adopt aforementioned arrangements arylacetamides azabicyclo bicycles bicyclo bicyclononanone bicyclononanones carbonyl diazabicycles diazabicyclononanones dipyridyl enantiomers geometries heterocyclic isoquinolines ketocyclazocine n7 nonan oxa pharmacophoric pm3 protonated protonation semiempirical stereoisomers substituents unravel	atf6 beyond bzip elucidate endoplasmic expands inducers intramembrane knockouts l4 mammals members microarray proteolysis proteolytic proteolytically recognition reticulum rnai screens similarity spectrum stimulate subfamily thought tumorigenesis unfolded upr
Tagcloud (Difference) ?		adopt aforementioned arrangements arylacetamides azabicyclo bicycles bicyclo bicyclononanone bicyclononanones carbonyl diazabicycles diazabicyclononanones dipyridyl enantiomers geometries heterocyclic isoquinolines ketocyclazocine n7 nonan oxa pharmacophoric pm3 protonated protonation semiempirical stereoisomers substituents unravel	atf6 beyond bzip elucidate endoplasmic expands inducers intramembrane knockouts l4 mammals members microarray proteolysis proteolytic proteolytically recognition reticulum rnai screens similarity spectrum stimulate subfamily thought tumorigenesis unfolded upr
Tagcloud (Intersection) ?