PAIP2

Description		poly(A) binding protein interacting protein 2
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GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	MRNA Regulatory Element Binding Translation Repressor Activity MRNA Binding Protein Binding Translation Repressor Activity
	Biological Process	Translation Regulation Of Translation Spermatogenesis Memory Negative Regulation Of Translation Negative Regulation Of Translational Initiation Regulation Of Long-term Synaptic Potentiation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Malaria ( 31844061)
Interacting Genes		6 interacting genes: APP ELAVL1 PABPC1 RPL11 TRIM54 UBR5
Entrez ID		51247
HPRD ID		05726
Ensembl ID		ENSG00000120727
Uniprot IDs		Q49AE6 Q9BPZ3
PDB IDs		1JGN 3KUS 3KUT
Enriched GO Terms of Interacting Partners?		Regulation Of Superoxide Anion Generation Positive Regulation Of Gene Expression Positive Regulation Of Superoxide Anion Generation Regulation Of Superoxide Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Translation Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Autophagosome Size Negative Regulation Of MRNA Catabolic Process RNA Stabilization MRNA Stabilization Negative Regulation Of Catabolic Process Ribonucleoprotein Complex Positive Regulation Of Macromolecule Biosynthetic Process Acetylcholine Receptor Activator Activity Positive Regulation Of Macromolecule Metabolic Process PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Endosome To Plasma Membrane Transport Vesicle Regulation Of Protein Metabolic Process Positive Regulation Of Biosynthetic Process Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Endothelin Production Regulation Of Reactive Oxygen Species Metabolic Process Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of RNA Catabolic Process MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Cytoplasmic Stress Granule Positive Regulation Of MRNA Metabolic Process RNA Binding Cytoplasm Protein Quality Control By The Ubiquitin-proteasome System Heterochromatin Boundary Formation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Regulation Of Protein Localization To Nucleus Astrocyte Activation Involved In Immune Response
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