PAIP2 and RPL11

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PAIP2	RPL11
Gene Name		poly(A) binding protein interacting protein 2	ribosomal protein L11
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleolus Cytosol Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	MRNA Binding Protein Binding Translation Repressor Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding Poly(A) RNA Binding
	Biological Process	Spermatogenesis Memory Negative Regulation Of Translational Initiation Regulation Of Long-term Synaptic Potentiation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation Translational Elongation Translational Termination Protein Targeting SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Protein Localization To Nucleus Ribosomal Large Subunit Biogenesis Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP ELAVL1 PABPC1 RPL11 UBR5	14 interactors: ARFGAP1 BLMH C12orf5 CAMK2B HP IGF1R KRT40 KRTAP10-7 LIG4 MDM2 NEDD8 PAIP2 PML STAT3
Entrez ID		51247	6135
HPRD ID		05726	10364
Ensembl ID		ENSG00000120727	ENSG00000142676
Uniprot IDs		Q9BPZ3	P62913 Q5VVD0
PDB IDs		1JGN 3KUS 3KUT	3J3B
Enriched GO Terms of Interacting Partners?		MRNA Stabilization MRNA Polyadenylation Regulation Of Translation RNA Polyadenylation Regulation Of MRNA Stability Regulation Of RNA Stability Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Translation MRNA Metabolic Process MRNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RNA 3'-end Processing Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Nuclear-transcribed MRNA Catabolic Process Synaptic Growth At Neuromuscular Junction MRNA Catabolic Process Cellular Macromolecule Catabolic Process RNA Catabolic Process Collateral Sprouting In Absence Of Injury Negative Regulation Of Histone H2A K63-linked Ubiquitination Intracellular Receptor Signaling Pathway Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translational Initiation Positive Regulation Of Cellular Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Protein K63-linked Ubiquitination Progesterone Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Axon Choice Point Recognition Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Neuron Remodeling Gene Expression 3'-UTR-mediated MRNA Stabilization Positive Regulation Of Catenin Import Into Nucleus Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Protein Import Into Nucleus, Translocation Positive Regulation Of Cellular Biosynthetic Process MRNA Processing Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Aromatic Compound Catabolic Process Regulation Of MRNA 3'-end Processing	Regulation Of Cell Death Response To Gamma Radiation Positive Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Immune System Process Regulation Of Apoptotic Process Enzyme Linked Receptor Protein Signaling Pathway Response To Ionizing Radiation Response To Radiation Response To Inorganic Substance Response To Stimulus Regulation Of Cell Cycle Process Response To Organic Substance Protein Localization To Nucleus Viral Process Response To Abiotic Stimulus Cellular Response To Growth Factor Stimulus Response To Growth Factor Acute-phase Response Positive Regulation Of Cell Death Negative Regulation Of Reactive Oxygen Species Metabolic Process Immune Response Defense Response Regulation Of Muscle Cell Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Cellular Response To Peptide Hormone Stimulus Negative Regulation Of Catalytic Activity Regulation Of Cell Proliferation Cellular Response To Peptide Response To Metal Ion Negative Regulation Of Cellular Protein Metabolic Process Response To Stress Negative Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Translation In Response To Oxidative Stress DNA Ligation Involved In DNA Recombination Cellular Response To UV-C Inactivation Of MAPKK Activity Cellular Response To Vitamin B1 Inhibitory G-protein Coupled Receptor Phosphorylation Somatic Stem Cell Maintenance Cellular Response To Stress Proteolysis Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint
Tagcloud ?		5l avian bicistronic bona closed compatible concomitantly explanation fide herpesvirus ie immediate ires leader manners marek mdv1 message micrornas mutagenesis neurovirulence pabp1 poly pool pp14 recruitment ribosome serotype virally	actinomycin biogenesis blunted blunting blunts caffeine chemotherapeutics combinatorial connected destabilize glioma indeed insults ly294 master mechanistic mimicked mtor nucleolar osteosarcoma pp242 rapamycin ribosome simultaneous stabilization temsirolimus triggered whereby wortmannin
Tagcloud (Difference) ?		5l avian bicistronic bona closed compatible concomitantly explanation fide herpesvirus ie immediate ires leader manners marek mdv1 message micrornas mutagenesis neurovirulence pabp1 poly pool pp14 recruitment serotype virally	actinomycin biogenesis blunted blunting blunts caffeine chemotherapeutics combinatorial connected destabilize glioma indeed insults ly294 master mechanistic mimicked mtor nucleolar osteosarcoma pp242 rapamycin simultaneous stabilization temsirolimus triggered whereby wortmannin
Tagcloud (Intersection) ?		ribosome