PHC2 and L3MBTL3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PHC2	L3MBTL3
Gene Name		polyhomeotic homolog 2 (Drosophila)	l(3)mbt-like 3 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Nucleus
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Molecular_function
	Biological Process	Multicellular Organismal Development Spermatogenesis	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Chromatin Modification Macrophage Differentiation Granulocyte Differentiation Erythrocyte Maturation
Pathways		Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS			Height ( 20881960 23563607 18391951)
Protein-Protein Interactions		68 interactors: AEN AFG3L2 AP1M1 BMI1 BSDC1 BYSL C1orf109 CARD9 CBX8 CRKL CSNK2B DRG1 ENKD1 FAM124A FAM13C FAM161A FAM74A1 FAM74A4 FHL3 GFI1B GRB2 HIST3H3 KAT5 KBTBD7 KDM1A KIFC3 L3MBTL3 LMO1 LMO2 LMO3 MAB21L3 MAGEB6 MAPK14 MAPK6 MAPKAPK2 MCM2 MCRS1 MFAP1 MORF4L2 NCK1 PCGF2 PCGF3 PCGF5 PHC1 PLK1 POLR2L PPP1R16B PRKAA1 PRPF31 RBM39 RPL7 RWDD2B SCMH1 SDCBP SFMBT1 SIAH1 SMAD3 SPATC1L SSX2IP SYT16 TAB1 THAP7 TMEM70 TRIM41 ZBTB24 ZGPAT ZMAT2 ZNF417	26 interactors: ASB6 BANP BYSL KDM1A LRRK2 LSM4 LZTR1 MAPK3 MAPK9 MORF4L1 MORF4L2 NGB OAZ3 PDE6G PHC2 PIK3R3 PLEKHF1 PLEKHF2 POLR2L PRKAA1 PRKAA2 SNRPB SP100 SUMO1P1 THRA TTC19
Entrez ID		1912	84456
HPRD ID		10340	11222
Ensembl ID		ENSG00000134686	ENSG00000198945
Uniprot IDs		B3KPJ4 Q8IXK0	Q96JM7
PDB IDs			1WJQ 1WJS 3UT1 4FL6 4L59
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Gene Expression Chromatin Organization Chromosome Organization Chromatin Modification Organelle Organization Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Phosphorus Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Phosphorylation Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Cellular Response To Stress Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Histone Modification Cellular Response To DNA Damage Stimulus Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Developmental Process Positive Regulation Of Signal Transduction Immune System Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Regulation Of Signal Transduction Anatomical Structure Development Response To Ionizing Radiation Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Immune System Development Regulation Of Cellular Protein Metabolic Process Regulation Of Intracellular Signal Transduction	Positive Regulation Of Autophagy Chromatin Modification Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Binding RNA Metabolic Process Regulation Of Autophagy Chromatin Organization Transcription, DNA-templated Positive Regulation Of Metabolic Process RNA Biosynthetic Process Regulation Of Lipid Metabolic Process Cellular Response To Stress Activation Of MAPK Activity Insulin Receptor Signaling Pathway Negative Regulation Of Protein Binding Negative Regulation Of Transport Chromosome Organization Gene Expression Positive Regulation Of MAP Kinase Activity Cellular Response To Insulin Stimulus Regulation Of Energy Homeostasis Regulation Of Apoptotic Process Positive Regulation Of Glycolytic Process Negative Regulation Of Intracellular Protein Transport Fatty Acid Homeostasis Positive Regulation Of Gene Expression Cellular Response To Organonitrogen Compound Regulation Of Cell Death Cellular Nitrogen Compound Metabolic Process Regulation Of Binding Regulation Of Circadian Rhythm Organelle Organization Response To Organonitrogen Compound Regulation Of Metabolic Process Activation Of Protein Kinase Activity Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity Nucleobase-containing Compound Metabolic Process Regulation Of MAP Kinase Activity Response To Insulin Negative Regulation Of Intracellular Transport Histone-serine Phosphorylation Regulation Of Signal Transduction Peptidyl-serine Phosphorylation Regulation Of Intracellular Signal Transduction Cellular Response To Peptide Hormone Stimulus Cellular Response To Hormone Stimulus Response To Stress Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Glucose Starvation
Tagcloud ?		ansa arene bent binuclear bp86 c6 cf3 chelate concurred conversions coordinative diphenylethane ga gaga gallium h5 hexamethylbenzene me2 me3 me6 mesitylene multinuclear olefinic ph2 polyisobutylene reactivities terphenyl univalent xylene
Tagcloud (Difference) ?		ansa arene bent binuclear bp86 c6 cf3 chelate concurred conversions coordinative diphenylethane ga gaga gallium h5 hexamethylbenzene me2 me3 me6 mesitylene multinuclear olefinic ph2 polyisobutylene reactivities terphenyl univalent xylene
Tagcloud (Intersection) ?