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EBF1 and ZNF521
Number of citations of the paper that reports this interaction (PMID
14630787
)
19
Data Source:
HPRD
(in vitro)
EBF1
ZNF521
Gene Name
early B-cell factor 1
zinc finger protein 521
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleus
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Metal Ion Binding
Protein Dimerization Activity
C2H2 Zinc Finger Domain Binding
DNA Binding
Protein Domain Specific Binding
Metal Ion Binding
Biological Process
Transcription, DNA-templated
Multicellular Organismal Development
Positive Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Multicellular Organismal Development
Cell Differentiation
Pathways
Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS
Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) (
23648065
)
Blood pressure (
21909110
)
Breast cancer (
23535729
23535733
)
Diastolic blood pressure (
21909115
)
Hypertension (
21909115
)
Obesity-related traits (
23251661
)
Systolic blood pressure (
21909115
)
Adverse response to lamotrigine and phenytoin (
22379998
)
Protein-Protein Interactions
6 interactors:
ATPAF2
CREBBP
HOMEZ
PAX5
ZNF423
ZNF521
5 interactors:
EBF1
GATA1
LYST
SMAD1
SMAD4
Entrez ID
1879
25925
HPRD ID
01256
18350
Ensembl ID
ENSG00000164330
ENSG00000198795
Uniprot IDs
Q9UH73
J3KTI4
Q96K83
PDB IDs
3LYR
3MQI
Enriched GO Terms of Interacting Partners
?
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Notch Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Proton-transporting ATP Synthase Complex Assembly
N-terminal Peptidyl-lysine Acetylation
Negative Regulation Of Cellular Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Germ-line Stem Cell Maintenance
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Histone H3-K9 Methylation
N-terminal Protein Amino Acid Acetylation
Positive Regulation Of Transcription, DNA-templated
Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Histone Methylation
Positive Regulation Of Gene Expression
Cell Differentiation
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
N-terminal Protein Amino Acid Modification
Regulation Of Cellular Response To Heat
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of BMP Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of Histone Methylation
Regulation Of Metabolic Process
Regulation Of DNA-templated Transcription In Response To Stress
Skeletal Muscle Cell Differentiation
Cellular Response To Heat
Multicellular Organismal Development
Transcription From RNA Polymerase II Promoter
SMAD Protein Complex Assembly
Cell Fate Commitment
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
BMP Signaling Pathway
Embryonic Pattern Specification
Wound Healing
Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis
Negative Regulation Of Cell Proliferation
Ureteric Bud Development
Mesonephric Tubule Development
Mesonephric Epithelium Development
Response To Wounding
Mesonephros Development
Transforming Growth Factor Beta Receptor Signaling Pathway
Mesoderm Development
Basophil Differentiation
Eosinophil Fate Commitment
Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway
Nephrogenic Mesenchyme Morphogenesis
Mast Cell Secretory Granule Organization
Kidney Epithelium Development
Transcription, DNA-templated
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Positive Regulation Of Cell Differentiation
Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Gastrulation
Eosinophil Differentiation
Nephrogenic Mesenchyme Development
Metanephric Mesenchyme Morphogenesis
Transcriptional Activation By Promoter-enhancer Looping
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Cell Death
Regulation Of Ossification
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Anatomical Structure Formation Involved In Morphogenesis
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Definitive Erythrocyte Differentiation
Embryo Development
Regulation Of Binding
Endocardial Cell Differentiation
Endosome Transport Via Multivesicular Body Sorting Pathway
Primary MiRNA Processing
RNA Metabolic Process
Osteoblast Fate Commitment
Tagcloud
?
collaborate
concert
coordinate
cues
decades
e2a
epigenetic
establish
establishing
extrinsic
fate
fates
foxo1
guide
ikaros
landscape
lineage
lineages
lock
loops
lymphopoiesis
modifiers
modify
pax
permissive
prime
pu
repress
runx1
Tagcloud (Difference)
?
collaborate
concert
coordinate
cues
decades
e2a
epigenetic
establish
establishing
extrinsic
fate
fates
foxo1
guide
ikaros
landscape
lineage
lineages
lock
loops
lymphopoiesis
modifiers
modify
pax
permissive
prime
pu
repress
runx1
Tagcloud (Intersection)
?