ZNF521 and LYST

Number of citations of the paper that reports this interaction (PMID 11984006)
18

Data Source:
BioGRID (two hybrid)

		ZNF521	LYST
Gene Name		zinc finger protein 521	lysosomal trafficking regulator
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytosol Endomembrane System Microtubule Cytoskeleton Extrinsic Component Of Membrane
	Molecular Function	DNA Binding Protein Domain Specific Binding Metal Ion Binding	Protein Binding Phospholipid Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development Cell Differentiation	Neutrophil Mediated Immunity T Cell Mediated Immunity Phospholipid Metabolic Process Microtubule-based Process Lysosome Organization Blood Coagulation Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Response To Drug Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus Phospholipid Homeostasis
Pathways
Drugs
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998)
Protein-Protein Interactions		5 interactors: EBF1 GATA1 LYST SMAD1 SMAD4	24 interactors: ATN1 CALM1 CELF4 CENPJ CNTROB CSNK2B DGCR14 DNAJC14 EFS ESRRA HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ YWHAZ ZNF521
Entrez ID		25925	1130
HPRD ID		18350	06060
Ensembl ID		ENSG00000198795	ENSG00000143669
Uniprot IDs		J3KTI4 Q96K83	Q99698
PDB IDs
Enriched GO Terms of Interacting Partners?		SMAD Protein Complex Assembly Cell Fate Commitment Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process BMP Signaling Pathway Embryonic Pattern Specification Wound Healing Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Negative Regulation Of Cell Proliferation Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Response To Wounding Mesonephros Development Transforming Growth Factor Beta Receptor Signaling Pathway Mesoderm Development Basophil Differentiation Eosinophil Fate Commitment Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Nephrogenic Mesenchyme Morphogenesis Mast Cell Secretory Granule Organization Kidney Epithelium Development Transcription, DNA-templated Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Gastrulation Eosinophil Differentiation Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Transcriptional Activation By Promoter-enhancer Looping Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Death Regulation Of Ossification Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Formation Involved In Morphogenesis Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Definitive Erythrocyte Differentiation Embryo Development Regulation Of Binding Endocardial Cell Differentiation Endosome Transport Via Multivesicular Body Sorting Pathway Primary MiRNA Processing RNA Metabolic Process Osteoblast Fate Commitment	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Mitochondrion Organization Protein Targeting Alternative MRNA Splicing, Via Spliceosome Regulation Of Mitochondrion Organization Centriole Replication Membrane Organization Gene Expression Protein Transport Centriole Assembly Establishment Of Protein Localization Epidermal Growth Factor Receptor Signaling Pathway Multicellular Organismal Development Centrosome Duplication ERBB Signaling Pathway Positive Regulation Of Transport Substantia Nigra Development Regulation Of Intracellular Transport Intrinsic Apoptotic Signaling Pathway Nervous System Development Positive Regulation Of Apoptotic Signaling Pathway MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Neural Nucleus Development Intracellular Protein Transport Centrosome Cycle Protein Localization Positive Regulation Of Intracellular Transport Apoptotic Process Establishment Of Localization In Cell Developmental Process Mitochondrial Translational Elongation Mitochondrial Translational Initiation Mitochondrial Translational Termination Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Programmed Cell Death Intracellular Transport Regulation Of Cellular Localization Cell Death Death Anatomical Structure Development Mitochondrial Translation System Development Midbrain Development Golgi Reassembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity RNA Splicing
Tagcloud ?			ataxin atp13a2 atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Difference) ?			ataxin atp13a2 atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Intersection) ?