EBF1 and HOMEZ

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EBF1	HOMEZ
Gene Name		early B-cell factor 1	homeobox and leucine zipper encoding
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleolus Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding Protein Dimerization Activity C2H2 Zinc Finger Domain Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity
	Biological Process	Transcription, DNA-templated Multicellular Organismal Development Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated
Pathways		Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) ( 23648065) Blood pressure ( 21909110) Breast cancer ( 23535729 23535733) Diastolic blood pressure ( 21909115) Hypertension ( 21909115) Obesity-related traits ( 23251661) Systolic blood pressure ( 21909115)
Protein-Protein Interactions		6 interactors: ATPAF2 CREBBP HOMEZ PAX5 ZNF423 ZNF521	31 interactors: AEN AES APITD1 DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPL9 SDCBP SH3RF2 SMYD1 SNRPB2 SUMO2 TCEB3 TRAF4 ZBTB7A
Entrez ID		1879	57594
HPRD ID		01256	12167
Ensembl ID		ENSG00000164330	ENSG00000215271
Uniprot IDs		Q9UH73	F8WCA3 Q8IX15
PDB IDs		3LYR 3MQI	2ECC 2YS9
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Notch Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Proton-transporting ATP Synthase Complex Assembly N-terminal Peptidyl-lysine Acetylation Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Germ-line Stem Cell Maintenance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Histone H3-K9 Methylation N-terminal Protein Amino Acid Acetylation Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Histone Methylation Positive Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia N-terminal Protein Amino Acid Modification Regulation Of Cellular Response To Heat Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of BMP Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Histone Methylation Regulation Of Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Skeletal Muscle Cell Differentiation Cellular Response To Heat Multicellular Organismal Development Transcription From RNA Polymerase II Promoter	Regulation Of Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Ionizing Radiation RNA Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Energy Homeostasis Positive Regulation Of Glycolytic Process Negative Regulation Of Cellular Metabolic Process Fatty Acid Homeostasis Biosynthetic Process Histone-serine Phosphorylation Positive Regulation Of Metabolic Process Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Regulation Of Cellular Process Chromatin Modification Negative Regulation Of TOR Signaling Protein Modification By Small Protein Conjugation Regulation Of MAPK Cascade Histone Exchange Cholesterol Biosynthetic Process Insulin Receptor Signaling Pathway Positive Regulation Of Autophagy Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Histone Phosphorylation Translational Elongation Histone Modification Sterol Biosynthetic Process Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Regulation Of RNA Metabolic Process Anion Homeostasis Chromatin Remodeling
Tagcloud ?		collaborate concert coordinate cues decades e2a epigenetic establish establishing extrinsic fate fates foxo1 guide ikaros landscape lineage lineages lock loops lymphopoiesis modifiers modify pax permissive prime pu repress runx1
Tagcloud (Difference) ?		collaborate concert coordinate cues decades e2a epigenetic establish establishing extrinsic fate fates foxo1 guide ikaros landscape lineage lineages lock loops lymphopoiesis modifiers modify pax permissive prime pu repress runx1
Tagcloud (Intersection) ?