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EBF1
Gene Name
early B-cell factor 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Metal Ion Binding
Protein Dimerization Activity
C2H2 Zinc Finger Domain Binding
Biological Process
Transcription, DNA-templated
Multicellular Organismal Development
Positive Regulation Of Transcription, DNA-templated
Pathways
Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS
Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) (
23648065
)
Blood pressure (
21909110
)
Breast cancer (
23535729
23535733
)
Diastolic blood pressure (
21909115
)
Hypertension (
21909115
)
Obesity-related traits (
23251661
)
Systolic blood pressure (
21909115
)
Protein-protein Interactions
6 interactors:
ATPAF2
CREBBP
HOMEZ
PAX5
ZNF423
ZNF521
Entrez ID
1879
HPRD ID
01256
Ensembl ID
ENSG00000164330
Uniprot IDs
Q9UH73
PDB IDs
3LYR
3MQI
Enriched GO Terms of Interacting Partners
?
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Notch Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Proton-transporting ATP Synthase Complex Assembly
N-terminal Peptidyl-lysine Acetylation
Negative Regulation Of Cellular Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Germ-line Stem Cell Maintenance
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Histone H3-K9 Methylation
N-terminal Protein Amino Acid Acetylation
Positive Regulation Of Transcription, DNA-templated
Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Histone Methylation
Positive Regulation Of Gene Expression
Cell Differentiation
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
N-terminal Protein Amino Acid Modification
Regulation Of Cellular Response To Heat
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of BMP Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of Histone Methylation
Regulation Of Metabolic Process
Regulation Of DNA-templated Transcription In Response To Stress
Skeletal Muscle Cell Differentiation
Cellular Response To Heat
Multicellular Organismal Development
Transcription From RNA Polymerase II Promoter
Tagcloud
?
collaborate
concert
coordinate
cues
decades
e2a
epigenetic
establish
establishing
extrinsic
fate
fates
foxo1
guide
ikaros
landscape
lineage
lineages
lock
loops
lymphopoiesis
modifiers
modify
pax
permissive
prime
pu
repress
runx1