CRIP2 and GATA6

Number of citations of the paper that reports this interaction (PubMedID 12530967)
0

Data Source:
HPRD (in vivo, in vitro)

		CRIP2	GATA6
Description		cysteine rich protein 2	GATA binding protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Cell Cortex	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Nuclear Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Sequence-specific DNA Binding Metal Ion Binding NFAT Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Hemopoiesis	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Liver Development Sebaceous Gland Cell Differentiation Regulation Of Antimicrobial Humoral Response Outflow Tract Septum Morphogenesis Atrioventricular Node Development Sinoatrial Node Development Type B Pancreatic Cell Differentiation Pancreatic A Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Phospholipid Metabolic Process Endodermal Cell Fate Determination Male Gonad Development Response To Xenobiotic Stimulus Anatomical Structure Morphogenesis Gene Expression Regulation Of Gene Expression Cardiac Muscle Hypertrophy In Response To Stress Cell Differentiation Epithelial Cell Differentiation Pancreas Development Response To Retinoic Acid Negative Regulation Of Transforming Growth Factor Beta1 Production Negative Regulation Of Transforming Growth Factor Beta2 Production Tube Morphogenesis Endodermal Cell Differentiation Atrioventricular Canal Development Negative Regulation Of Apoptotic Process Response To Estrogen Cell Fate Commitment Positive Regulation Of Angiogenesis Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Development Animal Organ Formation System Development Cardiac Muscle Tissue Development Stem Cell Differentiation Smooth Muscle Cell Differentiation Cardiac Muscle Cell Differentiation Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Heart Contraction Lung Saccule Development Club Cell Differentiation Type II Pneumocyte Differentiation Intestinal Epithelial Cell Differentiation Cardiac Vascular Smooth Muscle Cell Differentiation G1 To G0 Transition Involved In Cell Differentiation Response To Growth Factor Cellular Response To Gonadotropin Stimulus Cellular Response To Hypoxia Cellular Response To BMP Stimulus Skin Epidermis Development Positive Regulation Of Cardiac Muscle Myoblast Proliferation Negative Regulation Of Sebum Secreting Cell Proliferation
Pathways			Surfactant metabolism Cardiogenesis Formation of definitive endoderm Formation of definitive endoderm Factors involved in megakaryocyte development and platelet production Developmental Lineage of Multipotent Pancreatic Progenitor Cells
Drugs
Diseases
GWAS			Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Diverticular disease ( 30177863) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) LDL cholesterol ( 25961943) Lung function (FEV1/FVC) ( 30804560) Resting heart rate ( 27798624) Severe progression in rheumatoid arthritis ( 29065906) Tuberculosis ( 20694014)
Interacting Genes		19 interacting genes: APP ATN1 ATP1B1 ATXN1 CDC42 ERBB2 GADD45G GATA4 GATA6 KLF10 NOTCH3 OSGEP PCYT2 PRKG1 PTPN13 SMN1 SPRY2 SRF TK1	8 interacting genes: CRIP2 EP300 HHEX KLF2 KPNA3 MED1 NKX2-1 OGT
Entrez ID		1397	2627
HPRD ID		03113	09043
Ensembl ID		ENSG00000182809	ENSG00000141448
Uniprot IDs		P52943	Q92908
PDB IDs		2CU8
Enriched GO Terms of Interacting Partners?		Developmental Growth Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Neuron Projection Development Regulation Of Multicellular Organismal Process Developmental Cell Growth Cardiac Vascular Smooth Muscle Cell Differentiation Developmental Growth Involved In Morphogenesis Tube Morphogenesis NFAT Protein Binding Atrioventricular Node Development Cardiocyte Differentiation Muscle Tissue Development Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of Muscle Contraction Cell Growth Involved In Cardiac Muscle Cell Development Cell Fate Commitment Vascular Associated Smooth Muscle Cell Differentiation Cardiac Muscle Tissue Development Negative Regulation Of Transcription By RNA Polymerase II Atrioventricular Canal Development Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Animal Organ Development Regulation Of Multicellular Organismal Development Intestinal Epithelial Cell Differentiation Forebrain Development System Development Wound Healing Regulation Of MiRNA Transcription Regulation Of Developmental Process Developmental Process System Process Protein Kinase Binding Positive Regulation Of MAPK Cascade Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MiRNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Muscle System Process Positive Regulation Of Growth Collateral Sprouting Associative Learning Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Biosynthetic Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Metabolic Process Hemopoiesis Protein-DNA Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Developmental Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Chromatin Positive Regulation Of RNA Metabolic Process Cellular Developmental Process Regionalization Response To Hormone Protein Localization To Organelle Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Biosynthetic Process Regulation Of Developmental Process Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Cell Development Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Biosynthetic Process Megakaryocyte Development RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Histone Acetyltransferase Complex Negative Regulation Of Metabolic Process Intracellular Protein Localization Lung Epithelial Cell Differentiation Lung Cell Differentiation DNA-binding Transcription Factor Binding Protein Localization To Nucleus RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Multicellular Organismal Process Regulation Of Signal Transduction Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Brain Development Nuclear Receptor Binding Rhythmic Process
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