CRIP2 and PTPN13

Number of citations of the paper that reports this interaction (PMID 12839623)
9

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		CRIP2	PTPN13
Gene Name		cysteine-rich protein 2	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
Image
Gene Ontology Annotations	Cellular Component	Cell Cortex Extracellular Matrix	Nucleus Cytoplasm Cytoskeleton Plasma Membrane Lamellipodium Neuron Projection Cell Body Extracellular Vesicular Exosome
	Molecular Function	Zinc Ion Binding	Protein Tyrosine Phosphatase Activity Protein Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding
	Biological Process	Positive Regulation Of Cell Proliferation Hemopoiesis	Protein Dephosphorylation Regulation Of Phosphatidylinositol 3-kinase Signaling Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: APP ATN1 ATP1B1 ATXN1 GADD45G GATA4 GATA6 KLF10 NOTCH3 OSGEP PCYT2 PRKG1 PTPN13 SMN1 SPRY2 SRF TK1	21 interactors: APC ARHGAP29 BRD7 CRIP2 CTNNB1 EFNB1 EFNB2 FADD FAS FASLG GHR NFKBIA NGFR NGFRAP1 PDLIM4 PKN2 PLEKHA1 PRKACA RAPGEF6 TRIP6 YWHAZ
Entrez ID		1397	5783
HPRD ID		03113	02602
Ensembl ID		ENSG00000182809	ENSG00000163629
Uniprot IDs		P52943	Q12923
PDB IDs		2CU8	1D5G 1Q7X 1WCH 2M0Z 2M10 3LNX 3LNY 3PDZ
Enriched GO Terms of Interacting Partners?		Blood Coagulation Hemostasis Multicellular Organismal Development Regulation Of Body Fluid Levels System Development Wound Healing Regulation Of Muscle Contraction Positive Regulation Of Cardioblast Differentiation Developmental Process Response To Wounding Tube Development Organ Development Cardiac Vascular Smooth Muscle Cell Differentiation Anatomical Structure Development RNA Metabolic Process Lung Development Respiratory Tube Development Associative Learning Muscle System Process Developmental Growth Negative Regulation Of Cellular Metabolic Process Respiratory System Development Regulation Of Developmental Growth Cell Fate Commitment Nucleobase-containing Compound Metabolic Process Cardiac Muscle Hypertrophy In Response To Stress Coronary Vasculature Development Cardiac Muscle Cell Differentiation Response To Abiotic Stimulus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Vascular Smooth Muscle Cell Differentiation Formation Of Primary Germ Layer Intestinal Epithelial Cell Differentiation Cardiocyte Differentiation Relaxation Of Muscle Cellular Response To Gonadotropin Stimulus Digestive Tract Development Cardiac Muscle Hypertrophy Cellular Nitrogen Compound Metabolic Process Learning Cardiac Chamber Development Muscle Hypertrophy Regulation Of Transcription From RNA Polymerase II Promoter Digestive System Development Positive Regulation Of Developmental Growth Positive Regulation Of Cardiac Muscle Cell Proliferation Cell Differentiation Gene Expression Forebrain Development	Signal Transduction Signaling Cell Communication Apoptotic Process Programmed Cell Death Cell Death Death Cellular Response To Stimulus Regulation Of Signal Transduction Regulation Of Myeloid Cell Differentiation Regulation Of Cell Proliferation Regulation Of Signaling Cell Surface Receptor Signaling Pathway Necroptotic Signaling Pathway Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cell Death Positive Regulation Of Signal Transduction Response To Stimulus Regulation Of Intracellular Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Apoptotic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Cell Adhesion T Cell Differentiation In Thymus Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Cell Junction Assembly Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cell Death Cell-cell Junction Organization Motor Neuron Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Cellular Process Activation Of Cysteine-type Endopeptidase Activity Regulation Of Cellular Protein Metabolic Process Extrinsic Apoptotic Signaling Pathway Zymogen Activation Regulation Of Myeloid Leukocyte Differentiation Necroptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Tagcloud ?			adenocarcinomas atxn2 biology consistently couple deregulation dhx9 driver exome hundreds kras mutations myof never overlap preferentially recurrent respective rps6kb2 seq sequenced smokers somatic sp1 sptan1 stratification targetable ten thousands
Tagcloud (Difference) ?			adenocarcinomas atxn2 biology consistently couple deregulation dhx9 driver exome hundreds kras mutations myof never overlap preferentially recurrent respective rps6kb2 seq sequenced smokers somatic sp1 sptan1 stratification targetable ten thousands
Tagcloud (Intersection) ?