DNTT and DNTTIP2

Number of citations of the paper that reports this interaction (PubMedID 12786946)
0

Data Source:
HPRD (two hybrid, in vitro)

		DNTT	DNTTIP2
Description		DNA nucleotidylexotransferase	deoxynucleotidyltransferase terminal interacting protein 2
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GO Annotations	Cellular Component	Chromatin Euchromatin Nucleus Nucleoplasm Cytosol Nuclear Matrix	Nucleus Nucleoplasm Chromosome Nucleolus Small-subunit Processome
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity DNA Nucleotidylexotransferase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity DNA Polymerase Activity Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	DNA Metabolic Process DNA Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Modification Response To ATP DNA Biosynthetic Process	RNA Processing Ribosomal Small Subunit Biogenesis
Pathways
Drugs		2',3'-Dideoxyadenosine triphosphate
Diseases
GWAS			Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome ( 31991592)
Interacting Genes		9 interacting genes: ABTB2 DNTTIP1 DNTTIP2 MEI4 PCNA PRPF19 REL TCF4 XRCC6	18 interacting genes: CAVIN1 CEP70 DNTT ESR1 ESR2 H2AC25 H2BC1 H3C15 H4C16 PCNA PICK1 PPARG RBPMS RNF10 RNF8 RXRA SPP1 TULP3
Entrez ID		1791	30836
HPRD ID		08925	09994
Ensembl ID		ENSG00000107447	ENSG00000067334
Uniprot IDs		P04053	Q5QJE6
PDB IDs		2COE 5W4E	7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		Damaged DNA Binding DNA End Binding DNA Metabolic Process Telomere Maintenance Chromosome Organization Double-strand Break Repair Via Nonhomologous End Joining Ku70:Ku80 Complex Chromosome PCNA Complex PCNA-p21 Complex Replisome DNA Polymerase Processivity Factor Activity Mitotic Telomere Maintenance Via Semi-conservative Replication Dinucleotide Insertion Or Deletion Binding Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Beta-catenin-TCF7L2 Complex Negative Regulation Of Skeletal Muscle Tissue Growth	Nuclear Receptor Activity DNA Binding Enzyme Binding Nuclear Steroid Receptor Activity Structural Constituent Of Chromatin Nuclear Receptor-mediated Signaling Pathway Nuclear Estrogen Receptor Activity DNA Binding Domain Binding Nucleosome Nucleosome Organization Transcription Coregulator Binding Positive Regulation Of Lipoprotein Transport Nucleoplasm Chromatin Organization Hormone-mediated Signaling Pathway LBD Domain Binding Identical Protein Binding Chromosome, Telomeric Region Chromatin Remodeling Protein-DNA Complex Assembly Chromatin Regulation Of DNA-templated Transcription Estrogen Response Element Binding Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Regulation Of RNA Biosynthetic Process Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Intracellular Receptor Signaling Pathway Positive Regulation Of Lipid Transport Chromatin Binding Response To Lipid Regulation Of RNA Metabolic Process Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of DNA-templated Transcription Protein Localization To Chromosome Monocyte Differentiation Sperm DNA Condensation Nucleosome Disassembly Nucleosome Assembly Response To Estradiol Negative Regulation Of RNA Biosynthetic Process Protein-DNA Complex Disassembly Estrogen Receptor Signaling Pathway Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II Androgen Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process
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