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DNTT

Description DNA nucleotidylexotransferase
Image
GO Annotations Cellular Component
  • Chromatin
  • Euchromatin
  • Nucleus
  • Nucleoplasm
  • Cytosol
  • Nuclear Matrix
Molecular Function
  • DNA Binding
  • DNA-directed DNA Polymerase Activity
  • DNA Nucleotidylexotransferase Activity
  • Protein Binding
  • Transferase Activity
  • Nucleotidyltransferase Activity
  • DNA Polymerase Activity
  • Metal Ion Binding
Biological Process
  • DNA Metabolic Process
  • DNA Repair
  • Double-strand Break Repair Via Nonhomologous End Joining
  • DNA Modification
  • Response To ATP
  • DNA Biosynthetic Process
Pathways
Drugs
  • 2',3'-Dideoxyadenosine triphosphate
Diseases
GWAS
Novel Interacting Genes 1 novel interacting genes: TLL2
Interacting Genes 9 interacting genes: ABTB2 DNTTIP1 DNTTIP2 MEI4 PCNA PRPF19 REL TCF4 XRCC6
Entrez ID 1791
HPRD ID 08925
Ensembl ID ENSG00000107447
Uniprot IDs P04053
PDB IDs 2COE 5W4E
Enriched GO Terms of Interacting Partners?
  • Damaged DNA Binding
  • DNA End Binding
  • DNA Metabolic Process
  • Telomere Maintenance
  • Chromosome Organization
  • Double-strand Break Repair Via Nonhomologous End Joining
  • Ku70:Ku80 Complex
  • Chromosome
  • PCNA Complex
  • PCNA-p21 Complex
  • Replisome
  • DNA Polymerase Processivity Factor Activity
  • Mitotic Telomere Maintenance Via Semi-conservative Replication
  • Dinucleotide Insertion Or Deletion Binding
  • Purine-specific Mismatch Base Pair DNA N-glycosylase Activity
  • Beta-catenin-TCF7L2 Complex
  • Negative Regulation Of Skeletal Muscle Tissue Growth
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