DNTT and DNTTIP1

Number of citations of the paper that reports this interaction (PubMedID 11473582)
0

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		DNTT	DNTTIP1
Description		DNA nucleotidylexotransferase	deoxynucleotidyltransferase terminal interacting protein 1
Image
GO Annotations	Cellular Component	Chromatin Euchromatin Nucleus Nucleoplasm Cytosol Nuclear Matrix	Histone Deacetylase Complex Nucleus Nucleoplasm Chromosome Nucleolus
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity DNA Nucleotidylexotransferase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity DNA Polymerase Activity Metal Ion Binding	DNA Binding Protein Binding Nucleosome Binding Protein Homodimerization Activity
	Biological Process	DNA Metabolic Process DNA Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Modification Response To ATP DNA Biosynthetic Process
Pathways			Negative Regulation of CDH1 Gene Transcription
Drugs		2',3'-Dideoxyadenosine triphosphate
Diseases
GWAS			Mean platelet volume ( 27863252 32888494) Temporal pole volume ( 31530798)
Interacting Genes		9 interacting genes: ABTB2 DNTTIP1 DNTTIP2 MEI4 PCNA PRPF19 REL TCF4 XRCC6	12 interacting genes: ANP32B DNTT E2F6 EAF1 HMBOX1 HOMEZ KDM1A MAGEA6 MFAP1 PICK1 TRIM55 TRIM63
Entrez ID		1791	116092
HPRD ID		08925	16831
Ensembl ID		ENSG00000107447	ENSG00000101457
Uniprot IDs		P04053	Q9H147
PDB IDs		2COE 5W4E	2MWI 4D6K 6Z2J 6Z2K
Enriched GO Terms of Interacting Partners?		Damaged DNA Binding DNA End Binding DNA Metabolic Process Telomere Maintenance Chromosome Organization Double-strand Break Repair Via Nonhomologous End Joining Ku70:Ku80 Complex Chromosome PCNA Complex PCNA-p21 Complex Replisome DNA Polymerase Processivity Factor Activity Mitotic Telomere Maintenance Via Semi-conservative Replication Dinucleotide Insertion Or Deletion Binding Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Beta-catenin-TCF7L2 Complex Negative Regulation Of Skeletal Muscle Tissue Growth	Nucleus Telomeric DNA Binding
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