CADPS2

Description		calcium dependent secretion activator 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Centrosome Cytoskeleton Cilium Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Ciliary Basal Body Presynaptic Membrane Cell Projection Synapse Postsynaptic Membrane Parallel Fiber To Purkinje Cell Synapse Presynapse Glutamatergic Synapse
	Molecular Function	Lipid Binding Metal Ion Binding
	Biological Process	Exocytosis Cellular Response To Starvation Protein Transport Synaptic Vesicle Exocytosis Synaptic Vesicle Priming Positive Regulation Of Exocytosis Hematopoietic Stem Cell Homeostasis Dense Core Granule Exocytosis
Pathways
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Adult body size ( 32376654) Attention deficit hyperactivity disorder ( 30478444 32279069) Brain structure ( 20171287) General risk tolerance (MTAG) ( 30643258) Menarche (age at onset) ( 25231870) Number of sexual partners ( 30643258) Serum sulfate level ( 27412988) Smoking status (ever vs never smokers) ( 30643258) Waist circumference ( 28552196)
Interacting Genes		18 interacting genes: BDNF DMD DRD2 MEGF10 SRPK2 TMEM132D TSPOAP1 TTC3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2U UBE2W WDR4
Entrez ID		93664
HPRD ID		12996
Ensembl ID		ENSG00000081803
Uniprot IDs		B7ZM57 Q86UW7 X5D2D9 X5D7B2 X5D8X0 X5DNG0
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Ubiquitin-protein Transferase Activity Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Post-translational Protein Modification Protein Monoubiquitination Proteolysis Involved In Protein Catabolic Process Protein K11-linked Ubiquitination Protein Modification Process Transferase Activity ATP Binding Macromolecule Catabolic Process Proteolysis Nucleotide Binding Catabolic Process Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Negative Regulation Of TORC1 Signaling Protein K63-linked Ubiquitination TOR Signaling Proteasomal Protein Catabolic Process Negative Regulation Of TOR Signaling Regulation Of TORC1 Signaling Positive Regulation Of Protein Polyubiquitination Protein K6-linked Ubiquitination Protein Catabolic Process Regulation Of Protein Polyubiquitination Ubiquitin Protein Ligase Activity Regulation Of TOR Signaling Macromolecule Metabolic Process DNA Damage Response DNA Repair Positive Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway G Protein-coupled Receptor Complex Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production TRNA Methyltransferase Activator Activity TRNA (m7G46) Methyltransferase Complex Lateral Plasma Membrane Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Sodium Ion Transport Cellular Response To Nutrient Levels Protein Autoubiquitination Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission
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