NAP1L1 and CHORDC1

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		NAP1L1	CHORDC1
Description		nucleosome assembly protein 1 like 1	cysteine and histidine rich domain containing 1
Image
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Membrane Melanosome
	Molecular Function	Chromatin Binding RNA Binding Protein Binding Histone Binding Histone Chaperone Activity	Protein Binding ATP Binding Zinc Ion Binding ADP Binding Metal Ion Binding Hsp90 Protein Binding
	Biological Process	DNA Replication Nucleosome Assembly Nervous System Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of Neural Precursor Cell Proliferation	Protein Folding Regulation Of Centrosome Duplication Centrosome Duplication Regulation Of Cellular Response To Heat
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189)	Basophil count ( 32888494) Basophil percentage of white cells ( 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes		34 interacting genes: ANKRD23 C1QTNF9 CHORDC1 CREBBP CSNK2A1 CSNK2B DLST DYRK1A EP300 ERCC6 FSD1 GAS2L2 H1-1 H4C1 HBA1 HMGB2 HSPB1 ISG15 LINC01554 MED10 MTNR1A NAP1L2 NR2F6 OGT POT1 RPL23 RPL23A RPS15 SNCA SP1 SUMO2 TERF1 TP53 TPX2	7 interacting genes: HSP90AA1 HSP90AB1 NAP1L1 PAK1 PPP5C TCAP XPO1
Entrez ID		4673	26973
HPRD ID		01248	05072
Ensembl ID		ENSG00000187109	ENSG00000110172
Uniprot IDs		B7Z2V4 F5H4R6 F8W543 P55209 Q9H2B0	E9PPQ5 Q9UHD1
PDB IDs		7BP5 7UN3 7UN6	2YRT
Enriched GO Terms of Interacting Partners?		Rhythmic Process Regulation Of Protein Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Nucleoplasm Negative Regulation Of DNA Metabolic Process Nucleus Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cellular Response To Stress Regulation Of Cellular Response To Heat Transcription Coactivator Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Histone H3K27 Acetyltransferase Activity Tau Protein Binding Negative Regulation Of Cellular Component Organization Negative Regulation Of Microtubule Polymerization Or Depolymerization Histone H3K18 Acetyltransferase Activity Double-strand Break Repair N-terminal Peptidyl-lysine Acetylation Chromatin Remodeling Cellular Component Assembly Peptide Lactyltransferase (CoA-dependent) Activity Chromatin Organization Regulation Of Cellular Component Organization Protein Localization To Organelle Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Double-strand Break Repair Via Nonhomologous End Joining Symbiont-mediated Disruption Of Host Cell PML Body Circadian Rhythm Negative Regulation Of Telomere Maintenance Via Telomerase Cellular Response To Actinomycin D Negative Regulation Of Proteolysis Positive Regulation Of Metabolic Process Histone Acetyltransferase Complex Negative Regulation Of Catabolic Process Regulation Of Proteolysis Regulation Of Microtubule-based Process Response To Actinomycin D Regulation Of Primary Metabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Amide Metabolic Process Regulation Of Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Chromatin DNA Binding Regulation Of Protein-containing Complex Assembly Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of G1 To G0 Transition	Protein Folding Chaperone Complex Tau Protein Binding Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone Protein-containing Complex TPR Domain Binding Telomerase Holoenzyme Complex Assembly Melanosome Chaperone-mediated Protein Complex Assembly Telomere Maintenance Via Telomerase DNA Polymerase Binding Axonal Growth Cone RNA-templated DNA Biosynthetic Process MHC Class II Protein Complex Binding Disordered Domain Specific Binding Telomere Maintenance Via Telomere Lengthening Skeletal Muscle Contraction ATP-dependent Protein Folding Chaperone Positive Regulation Of Nitric Oxide Biosynthetic Process RNA Binding DNA Metabolic Process Positive Regulation Of Nitric Oxide Metabolic Process Cellular Response To Heat Protein Folding Chaperone Regulation Of Protein Localization Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Neuronal Cell Body Heat Shock Protein Binding Regulation Of Protein Catabolic Process CTP Binding DATP Binding Positive Regulation Of Protein Polymerization Striated Muscle Contraction Response To Unfolded Protein Response To Heat Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Response To Alkaloid DNA Biosynthetic Process Telomere Maintenance Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding HSP90-CDC37 Chaperone Complex Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Cellular Response To Triglyceride Titin-telethonin Complex Titin Z Domain Binding Sarcomerogenesis Protein-containing Complex Assembly
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