NAP1L1 and HBA1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		NAP1L1	HBA1
Gene Name		nucleosome assembly protein 1-like 1	hemoglobin, alpha 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Membrane Melanosome	Extracellular Region Cytosol Hemoglobin Complex Membrane Cytosolic Small Ribosomal Subunit Haptoglobin-hemoglobin Complex Extracellular Vesicular Exosome Endocytic Vesicle Lumen Blood Microparticle
	Molecular Function	Protein Binding Poly(A) RNA Binding	Peroxidase Activity Oxygen Transporter Activity Iron Ion Binding Protein Binding Oxygen Binding Heme Binding Haptoglobin Binding
	Biological Process	DNA Replication Nucleosome Assembly Positive Regulation Of Cell Proliferation	Receptor-mediated Endocytosis Positive Regulation Of Cell Death Oxygen Transport Bicarbonate Transport Response To Hydrogen Peroxide Hydrogen Peroxide Catabolic Process Small Molecule Metabolic Process Protein Heterooligomerization Oxidation-reduction Process
Pathways			O2/CO2 exchange in erythrocytes Scavenging of heme from plasma Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Mean corpuscular hemoglobin ( 20139978)
Protein-Protein Interactions		14 interactors: CREBBP CSNK2B DLST EP300 FSD1 HBA1 MED10 NR2F6 PHB POT1 SP1 TERF1 TP53 TPX2	9 interactors: ATP6AP1 CRYAB DAXX HBB NAP1L1 PTEN SPINK7 UBE3A UCHL5
Entrez ID		4673	3039
HPRD ID		01248	00784
Ensembl ID		ENSG00000187109	ENSG00000206172
Uniprot IDs		B3KV44 B7Z4K9 B7Z9C2 F8W543 P55209	D1MGQ2 P69905
PDB IDs			1A00 1A01 1A0U 1A0Z 1A3N 1A3O 1A9W 1ABW 1ABY 1AJ9 1B86 1BAB 1BBB 1BIJ 1BUW 1BZ0 1BZ1 1BZZ 1C7B 1C7C 1C7D 1CLS 1CMY 1COH 1DKE 1DXT 1DXU 1DXV 1FDH 1FN3 1G9V 1GBU 1GBV 1GLI 1GZX 1HAB 1HAC 1HBA 1HBB 1HBS 1HCO 1HDB 1HGA 1HGB 1HGC 1HHO 1IRD 1J3Y 1J3Z 1J40 1J41 1J7S 1J7W 1J7Y 1JY7 1K0Y 1K1K 1KD2 1LFL 1LFQ 1LFT 1LFV 1LFY 1LFZ 1LJW 1M9P 1MKO 1NEJ 1NIH 1NQP 1O1I 1O1J 1O1K 1O1L 1O1M 1O1N 1O1O 1O1P 1QI8 1QSH 1QSI 1QXD 1QXE 1R1X 1R1Y 1RPS 1RQ3 1RQ4 1RQA 1RVW 1SDK 1SDL 1SHR 1SI4 1THB 1UIW 1VWT 1XXT 1XY0 1XYE 1XZ2 1XZ4 1XZ5 1XZ7 1XZU 1XZV 1Y01 1Y09 1Y0A 1Y0C 1Y0D 1Y0T 1Y0W 1Y22 1Y2Z 1Y31 1Y35 1Y45 1Y46 1Y4B 1Y4F 1Y4G 1Y4P 1Y4Q 1Y4R 1Y4V 1Y5F 1Y5J 1Y5K 1Y7C 1Y7D 1Y7G 1Y7Z 1Y83 1Y85 1Y8W 1YDZ 1YE0 1YE1 1YE2 1YEN 1YEO 1YEQ 1YEU 1YEV 1YFF 1YG5 1YGD 1YGF 1YH9 1YHE 1YHR 1YIE 1YIH 1YVQ 1YVT 1YZI 1Z8U 2D5Z 2D60 2DN1 2DN2 2DN3 2DXM 2H35 2HBC 2HBD 2HBE 2HBF 2HBS 2HCO 2HHB 2HHD 2HHE 2M6Z 2W6V 2W72 2YRS 3B75 3D17 3D7O 3DUT 3HHB 3HXN 3IA3 3IC0 3IC2 3KMF 3NL7 3NMM 3ODQ 3ONZ 3OO4 3OO5 3OVU 3P5Q 3QJB 3QJC 3QJD 3QJE 3R5I 3S48 3S65 3S66 3SZK 3WCP 4FC3 4HHB 4L7Y 4MQC 4MQG 4MQH 4MQI 4MQJ 6HBW
Enriched GO Terms of Interacting Partners?		N-terminal Peptidyl-lysine Acetylation Mitotic Cell Cycle Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of DNA Replication Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomerase Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Positive Regulation Of Macromolecule Biosynthetic Process Chromosome Organization Positive Regulation Of Cellular Biosynthetic Process Positive Regulation By Host Of Viral Transcription Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Via Telomerase N-terminal Protein Amino Acid Acetylation Negative Regulation Of DNA Metabolic Process Rhythmic Process Cellular Response To Hypoxia Positive Regulation Of Metabolic Process Cellular Response To Decreased Oxygen Levels Mitotic Cell Cycle Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Telomerase Activity Cellular Response To Oxygen Levels Chromatin Organization Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of DNA Replication Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Telomere Maintenance Positive Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Androgen Receptor Signaling Pathway Notch Signaling Pathway Cellular Nitrogen Compound Metabolic Process RNA-dependent DNA Replication Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Cellular Metabolic Process Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of DNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Photoperiodism Entrainment Of Circadian Clock N-terminal Protein Amino Acid Modification Organelle Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Gene Expression	Regulation Of Proteolysis Regulation Of Cellular Protein Metabolic Process Prostate Gland Growth Forebrain Morphogenesis Regulation Of Protein Metabolic Process Regulation Of Protein Ubiquitination Androgen Receptor Signaling Pathway Negative Regulation Of Endopeptidase Activity Brain Morphogenesis Negative Regulation Of Peptidase Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Cellular Component Assembly Prostate Gland Development Regulation Of Endopeptidase Activity Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Protein Catabolic Process Protein Complex Assembly Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Sperm Entry Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Response To Inorganic Substance Organ Growth Regulation Of Metabolic Process Nucleosome Assembly Activation Of APC-Cdc20 Complex Activity Postsynaptic Density Assembly Negative Regulation Of Presynaptic Membrane Organization Positive Regulation Of Signal Transduction Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Response To Estradiol Regulation Of Catalytic Activity Response To Hydrogen Peroxide Chromatin Assembly Nucleosome Organization Negative Regulation Of Dendritic Spine Morphogenesis Nitric Oxide Transport Chromatin Assembly Or Disassembly Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Death
Tagcloud ?		arrays asf1a assembles assembly breaks caf chaperones clamp coupled elucidating faithfully h2a h2b loader nascent nucleosomal nucleosome nucleosomes p48 packaging pcna progress recapitulates replication replicative reproduces rfc strand synthesized	account alter auditory brainstem cerebrovascular cognitive derangement diabetics duration electrophysiological electrophysiologically evoked head infarcts lacunar latencies longer mellitus mri neither neuroradiologically niddm potentials regardless remaining scans taking v wave
Tagcloud (Difference) ?		arrays asf1a assembles assembly breaks caf chaperones clamp coupled elucidating faithfully h2a h2b loader nascent nucleosomal nucleosome nucleosomes p48 packaging pcna progress recapitulates replication replicative reproduces rfc strand synthesized	account alter auditory brainstem cerebrovascular cognitive derangement diabetics duration electrophysiological electrophysiologically evoked head infarcts lacunar latencies longer mellitus mri neither neuroradiologically niddm potentials regardless remaining scans taking v wave
Tagcloud (Intersection) ?