NUDT10 and RASSF1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		NUDT10	RASSF1
Gene Name		nudix (nucleoside diphosphate linked moiety X)-type motif 10	Ras association (RalGDS/AF-6) domain family member 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Microtubule Plasma Membrane Microtubule Cytoskeleton
	Molecular Function	Diphosphoinositol-polyphosphate Diphosphatase Activity Metal Ion Binding Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate Diphosphatase Activity Inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate Diphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase Activity Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity	Protein Binding Zinc Ion Binding Identical Protein Binding Protein N-terminus Binding
	Biological Process	Inositol Phosphate Metabolic Process Small Molecule Metabolic Process	Cellular Response To DNA Damage Stimulus Cell Cycle Arrest Ras Protein Signal Transduction Positive Regulation Of Protein Ubiquitination Protein Stabilization Negative Regulation Of Cell Cycle Arrest
Pathways		Synthesis of pyrophosphates in the cytosol Inositol phosphate metabolism
Drugs
Diseases
GWAS		Prostate cancer ( 18264097 18264098)
Protein-Protein Interactions		4 interactors: MTUS2 RASSF1 SNAPC5 TCF4	33 interactors: ATP2B4 AURKA AURKB C7orf25 C8orf33 CDC20 CNKSR1 DAXX DDB1 E4F1 EXOSC8 HRAS IGFBP5 KCNE3 KDM1A MAP1B MAP1S MAPK8 MDM2 MOAP1 MST1 NUDT10 RASSF5 SAV1 STK3 STK4 SUV39H1 SUV39H2 TNFRSF10A TNFRSF1A TUBB TUBG1 XPA
Entrez ID		170685	11186
HPRD ID		17651	05470
Ensembl ID		ENSG00000122824	ENSG00000068028
Uniprot IDs		Q8NFP7	Q9NS23
PDB IDs		3MCF	2KZU
Enriched GO Terms of Interacting Partners?		Cell Cycle Arrest Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus DNA-templated Transcription, Initiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Maintenance Of DNA Repeat Elements Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Embryonic Genitalia Morphogenesis Myoblast Fate Commitment Negative Regulation Of Cell Cycle Secretory Granule Localization Hindgut Morphogenesis Insulin Metabolic Process Hindgut Development Positive Regulation Of Protein Export From Nucleus Transcription Initiation From RNA Polymerase III Promoter Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Gluconeogenesis Regulation Of Triglyceride Biosynthetic Process Genitalia Morphogenesis Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Cell Cycle Arrest Embryonic Digestive Tract Morphogenesis Regulation Of Glycoprotein Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Protein Export From Nucleus Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Glucose Metabolic Process Regulation Of Triglyceride Metabolic Process Regulation Of Hormone Metabolic Process Regulation Of Cell Cycle Face Morphogenesis Negative Regulation Of Organ Growth Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Head Morphogenesis Oligodendrocyte Development Embryonic Digestive Tract Development Negative Regulation Of BMP Signaling Pathway Cell Cycle Process Regulation Of Oligodendrocyte Differentiation Myoblast Differentiation Transcription From RNA Polymerase III Promoter Regulation Of Gluconeogenesis Bone Mineralization Regulation Of Myelination Face Development Positive Regulation Of Stem Cell Differentiation	Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Regulation Of Cell Death Cell Death Death Regulation Of Protein Binding Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Apoptotic Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Death Hippo Signaling Response To Abiotic Stimulus Mitotic Cell Cycle Process Positive Regulation Of Protein Modification Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Organ Growth Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Primitive Hemopoiesis Mitotic Cell Cycle Peptidyl-serine Phosphorylation Positive Regulation Of Transferase Activity Cell Cycle Response To UV Negative Regulation Of Protein Binding Signal Transduction By Phosphorylation Cellular Response To Stress Regulation Of Signaling Positive Regulation Of Protein Kinase Activity Organelle Organization Endocardium Development Positive Regulation Of Kinase Activity Positive Regulation Of Signal Transduction Hepatocyte Apoptotic Process Positive Regulation Of Protein Phosphorylation Regulation Of Signal Transduction Negative Regulation Of Gene Expression Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cell Cycle Process Response To Light Stimulus Negative Regulation Of Developmental Growth Positive Regulation Of Cellular Metabolic Process
Tagcloud ?			bat braf cimp clinicopathological comparatively dapk develops discrete g15s gstp1 hierarchical hmlh1 inc india indian kras mint1 mint2 mint31 mononucleotide msi mss periodicals poorest rectal tp53 unfavorable v600e wiley
Tagcloud (Difference) ?			bat braf cimp clinicopathological comparatively dapk develops discrete g15s gstp1 hierarchical hmlh1 inc india indian kras mint1 mint2 mint31 mononucleotide msi mss periodicals poorest rectal tp53 unfavorable v600e wiley
Tagcloud (Intersection) ?