S100Z and S100A10

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		S100Z	S100A10
Name		S100 calcium binding protein Z	S100 calcium binding protein A10
Structure
GO Annotations	Cellular Component	None	Extracellular Region Cytoplasm Plasma Membrane Cell Surface Nuclear Matrix Extracellular Matrix Membrane Raft Extracellular Exosome RNA Polymerase II Transcription Regulator Complex Plasma Membrane Protein Complex AnxA2-p11 Complex
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Calcium-dependent Protein Binding	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Transmembrane Transporter Binding Calcium-dependent Protein Binding
	Biological Process	None	Membrane Raft Assembly Vesicle Budding From Membrane Positive Regulation Of Plasminogen Activation MRNA Transcription By RNA Polymerase II Positive Regulation Of GTPase Activity Positive Regulation Of Exocytosis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neurogenesis Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Plasma Membrane Repair
Pathways		None	Dissolution of Fibrin Clot
Drugs		None	Phenethyl Isothiocyanate
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690 ) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690 )	Asthma ( 31619474 ) Diverticular disease ( 30177863 ) Serum metabolite levels ( 33031748 ) Urinary metabolite levels in chronic kidney disease ( 29545352 ) Urinary metabolite ratios in chronic kidney disease ( 29545352 )
Interacting Genes		10 interacting genes: BEX3 OIP5 RASSF2 RBM48 S100A1 S100A10 S100A3 S100B S100P SNAPC5	23 interacting genes: ANXA2 ANXA7 BAD CBR3 CDK16 COPS6 CTSB DSCAM ERBB3 FSHR KCNK3 MLKL NANOS2 PLA2G4C PLG S100A3 S100Z SETDB1 SUMO2 TRPV5 TRPV6 USP2 ZGPAT
Entrez ID		170591	6281
HPRD ID		15291	00232
Ensembl ID		ENSG00000171643	ENSG00000197747
Uniprot IDs		Q8WXG8	P60903
PDB IDs		5HYD	1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH
GO Terms Enriched among Interactors		Calcium-dependent Protein Binding Calcium Ion Binding S100 Protein Binding Transition Metal Ion Binding Protein Homodimerization Activity	Calcium-dependent Protein Binding Calcium-dependent Phospholipid Binding Plasma Membrane S100 Protein Binding