TBC1D21 and EVI5L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TBC1D21	EVI5L
Description		TBC1 domain family member 21	ecotropic viral integration site 5 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cytoskeleton Cytoplasmic Vesicle Extracellular Exosome Sperm Midpiece
	Molecular Function	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Spermatogenesis Sperm Axoneme Assembly Cell Differentiation Flagellated Sperm Motility Plasma Membrane To Endosome Transport Sperm Mitochondrial Sheath Assembly Regulation Of Cilium Assembly	Positive Regulation Of GTPase Activity Negative Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916) LDL cholesterol levels in HIV infection ( 33109212)	Alanine aminotransferase levels ( 33547301) HIV-1 viral setpoint ( 20205591) Menarche (age at onset) ( 25231870)
Interacting Genes		29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10	15 interacting genes: A2M ANKRD36 AP1M1 CCDC185 DRC4 KRT79 LNX1 NUDT18 PRPF18 PSEN2 RAB10 RBM7 SRPK2 TBC1D21 ZNF648
Entrez ID		161514	115704
HPRD ID		15473	10044
Ensembl ID		ENSG00000167139	ENSG00000142459
Uniprot IDs		Q8IYX1	A0A384MR55 Q96CN4
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Skin Epidermis Supramolecular Fiber Organization Intermediate Filament Keratin Filament Cytoskeleton Structural Molecule Activity Regulation Of Cell Projection Organization Astrocyte Projection Morphogenesis Of An Epithelium Negative Regulation Of Cell Projection Organization Regulation Of Neurotransmitter Uptake Epithelial Cell Differentiation Tissue Morphogenesis Regulation Of Plasma Membrane Bounded Cell Projection Organization Axonemal A Tubule Inner Sheath	Flagellated Sperm Motility Cilium Movement Involved In Cell Motility Sperm Motility Cilium-dependent Cell Motility Epithelial Cilium Movement Involved In Extracellular Fluid Movement Cilium Movement Extracellular Transport 14-3-3 Protein Binding U2-type Post-spliceosomal Complex 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process Axoneme Assembly Negative Regulation Of Complement Activation, Lectin Pathway Generation Of Catalytic Spliceosome For Second Transesterification Step GDP Catabolic Process Interleukin-8 Binding Microtubule Bundle Formation Protein Localization To Basolateral Plasma Membrane Establishment Of Neuroblast Polarity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane 8-oxo-dGDP Phosphatase Activity Outer Dynein Arm Docking Complex
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