TBC1D21 and RIBC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TBC1D21	RIBC1
Description		TBC1 domain family member 21	RIB43A domain with coiled-coils 1
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cytoskeleton Cytoplasmic Vesicle Extracellular Exosome Sperm Midpiece	Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding	Protein Binding
	Biological Process	Spermatogenesis Sperm Axoneme Assembly Cell Differentiation Flagellated Sperm Motility Plasma Membrane To Endosome Transport Sperm Mitochondrial Sheath Assembly Regulation Of Cilium Assembly	Flagellated Sperm Motility
Pathways
Drugs
Diseases
GWAS		Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916) LDL cholesterol levels in HIV infection ( 33109212)	Bipolar disorder ( 31043756)
Interacting Genes		29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10	25 interacting genes: ATP6V0D2 BORCS6 CCNC EMILIN1 GOLGA2 GPSM1 HSF2BP KRT15 KRT31 KRT36 LDOC1 MISP MKRN3 MPPED2 OIP5 PFDN5 RINT1 TBC1D21 TEX11 TLE5 TOX2 TRIM23 TRIM27 USHBP1 VPS37C
Entrez ID		161514	158787
HPRD ID		15473	06553
Ensembl ID		ENSG00000167139	ENSG00000158423
Uniprot IDs		Q8IYX1	Q8N443
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Skin Epidermis Supramolecular Fiber Organization Intermediate Filament Keratin Filament Cytoskeleton Structural Molecule Activity Regulation Of Cell Projection Organization Astrocyte Projection Morphogenesis Of An Epithelium Negative Regulation Of Cell Projection Organization Regulation Of Neurotransmitter Uptake Epithelial Cell Differentiation Tissue Morphogenesis Regulation Of Plasma Membrane Bounded Cell Projection Organization Axonemal A Tubule Inner Sheath	Regulation Of Autophagy Establishment Of Localization In Cell Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Organization Identical Protein Binding Supramolecular Fiber Organization
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