TBC1D21 and PMF1-BGLAP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TBC1D21	PMF1-BGLAP
Description		TBC1 domain family member 21	PMF1-BGLAP readthrough
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cytoskeleton Cytoplasmic Vesicle Extracellular Exosome Sperm Midpiece
	Molecular Function	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Spermatogenesis Sperm Axoneme Assembly Cell Differentiation Flagellated Sperm Motility Plasma Membrane To Endosome Transport Sperm Mitochondrial Sheath Assembly Regulation Of Cilium Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916) LDL cholesterol levels in HIV infection ( 33109212)	Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
Interacting Genes		29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10	2 interacting genes: CATSPER1 TBC1D21
Entrez ID		161514	100527963
HPRD ID		15473
Ensembl ID		ENSG00000167139	ENSG00000260238
Uniprot IDs		Q8IYX1	A0A087WT04 Q6P1K2 U3KQ54
PDB IDs			5LSJ 5LSK 8PPR 8Q5H
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Skin Epidermis Supramolecular Fiber Organization Intermediate Filament Keratin Filament Cytoskeleton Structural Molecule Activity Regulation Of Cell Projection Organization Astrocyte Projection Morphogenesis Of An Epithelium Negative Regulation Of Cell Projection Organization Regulation Of Neurotransmitter Uptake Epithelial Cell Differentiation Tissue Morphogenesis Regulation Of Plasma Membrane Bounded Cell Projection Organization Axonemal A Tubule Inner Sheath	Sperm Motility Flagellated Sperm Motility Cilium Movement Involved In Cell Motility Cilium-dependent Cell Motility Cilium Movement Microtubule-based Movement Sperm Mitochondrial Sheath Assembly Male Gamete Generation CatSper Complex Gamete Generation Spermatogenesis Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Plasma Membrane To Endosome Transport Calcium-activated Cation Channel Activity Regulation Of Cilium Beat Frequency Microtubule-based Process Developmental Process Involved In Reproduction Sperm Principal Piece Sperm Axoneme Assembly Voltage-gated Calcium Channel Activity Cell Motility Regulation Of Cilium Movement Reproductive Process Regulation Of Microtubule-based Movement Axoneme Assembly Sperm Midpiece Microtubule Bundle Formation Calcium Channel Activity Regulation Of Cilium Assembly Acrosomal Vesicle Sperm Flagellum Monoatomic Ion Channel Complex Monoatomic Ion Channel Activity Cell Differentiation
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