EDA and LEPROTL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EDA	LEPROTL1
Gene Name		ectodysplasin A	leptin receptor overlapping transcript-like 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Trimer Endoplasmic Reticulum Membrane Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Apical Part Of Cell	Integral Component Of Membrane
	Molecular Function	Receptor Binding Tumor Necrosis Factor Receptor Binding Protein Binding
	Biological Process	Immune Response Cell-matrix Adhesion Signal Transduction Ectoderm Development Gene Expression Cell Differentiation Positive Regulation Of NF-kappaB Import Into Nucleus Odontogenesis Of Dentin-containing Tooth Pigmentation Positive Regulation Of NF-kappaB Transcription Factor Activity Salivary Gland Cavitation Hair Follicle Placode Formation Trachea Gland Development Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514)
Protein-Protein Interactions		15 interactors: ATP6V0C CYB561 DOLK EDA2R EDAR EMP3 FURIN GIMAP5 LEPROTL1 MAL NIPAL3 OSTC OSTCP1 PLN SEC22A	3 interactors: EDA KLRG1 MSR1
Entrez ID		1896	23484
HPRD ID		02347	09551
Ensembl ID		ENSG00000158813	ENSG00000104660
Uniprot IDs		Q92838	O95214 Q6FHL7
PDB IDs		1RJ7 1RJ8
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Interleukin-15 Production Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Cytotoxic T Cell Differentiation Negative Regulation Of Calcium-transporting ATPase Activity TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Dolichyl Monophosphate Biosynthetic Process Negative Regulation Of Hydrolase Activity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Nerve Growth Factor Production Negative Regulation Of Calcium Ion Binding Regulation Of The Force Of Heart Contraction By Cardiac Conduction Protein N-linked Glycosylation Via Asparagine Cell Death Death Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Membrane Raft Polarization Regulation Of Calcium-transporting ATPase Activity Negative Regulation Of Receptor Catabolic Process Adrenergic Receptor Signaling Pathway Involved In Heart Process Protein N-linked Glycosylation Positive Regulation Of JNK Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Nerve Growth Factor Processing G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Membrane Raft Localization Dolichyl Diphosphate Biosynthetic Process Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Signal Transduction Negative Regulation Of Calcium Ion Import Negative Regulation Of Transforming Growth Factor Beta Production Ectodermal Cell Differentiation Regulation Of JNK Cascade Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Relaxation Of Cardiac Muscle Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Salivary Gland Cavitation Regulation Of Stress-activated MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of ATPase Activity Regulation Of Relaxation Of Muscle Vesicle Fusion With Golgi Apparatus Regulation Of Cardiac Muscle Cell Membrane Potential Post-translational Protein Modification Transport	Trachea Gland Development Salivary Gland Cavitation Positive Regulation Of Cholesterol Storage Hair Follicle Placode Formation Lipoprotein Transport Positive Regulation Of NF-kappaB Import Into Nucleus Ectoderm Development Trachea Development Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Lipid Storage Plasma Lipoprotein Particle Clearance Positive Regulation Of Transcription Factor Import Into Nucleus Regulation Of NF-kappaB Import Into Nucleus Regulation Of Macrophage Derived Foam Cell Differentiation Salivary Gland Morphogenesis Salivary Gland Development Cellular Defense Response Regulation Of Lipid Storage Exocrine System Development Regulation Of Plasma Lipoprotein Particle Levels Sterol Transport Cholesterol Transport Immune Response Regulation Of Transcription Factor Import Into Nucleus Hair Follicle Development Hair Cycle Process Positive Regulation Of Protein Import Into Nucleus Hair Cycle Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport
Tagcloud ?		amplitudes asymmetry atypical comparison conductance contralateral depend discrepancy disinhibition electrodermal former frontal hemisphere idea left lesion motor neurophysiological phasic rejected right scl scls seem showing sweating tonic unrelated weakness
Tagcloud (Difference) ?		amplitudes asymmetry atypical comparison conductance contralateral depend discrepancy disinhibition electrodermal former frontal hemisphere idea left lesion motor neurophysiological phasic rejected right scl scls seem showing sweating tonic unrelated weakness
Tagcloud (Intersection) ?