EDA and OSTCP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EDA	OSTCP1
Gene Name		ectodysplasin A	oligosaccharyltransferase complex subunit pseudogene 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Trimer Endoplasmic Reticulum Membrane Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Apical Part Of Cell
	Molecular Function	Receptor Binding Tumor Necrosis Factor Receptor Binding Protein Binding
	Biological Process	Immune Response Cell-matrix Adhesion Signal Transduction Ectoderm Development Gene Expression Cell Differentiation Positive Regulation Of NF-kappaB Import Into Nucleus Odontogenesis Of Dentin-containing Tooth Pigmentation Positive Regulation Of NF-kappaB Transcription Factor Activity Salivary Gland Cavitation Hair Follicle Placode Formation Trachea Gland Development Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514)
Protein-Protein Interactions		15 interactors: ATP6V0C CYB561 DOLK EDA2R EDAR EMP3 FURIN GIMAP5 LEPROTL1 MAL NIPAL3 OSTC OSTCP1 PLN SEC22A	3 interactors: APP EDA SYNE4
Entrez ID		1896	202459
HPRD ID		02347	14130
Ensembl ID		ENSG00000158813	ENSG00000243775
Uniprot IDs		Q92838
PDB IDs		1RJ7 1RJ8
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Interleukin-15 Production Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Cytotoxic T Cell Differentiation Negative Regulation Of Calcium-transporting ATPase Activity TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Dolichyl Monophosphate Biosynthetic Process Negative Regulation Of Hydrolase Activity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Nerve Growth Factor Production Negative Regulation Of Calcium Ion Binding Regulation Of The Force Of Heart Contraction By Cardiac Conduction Protein N-linked Glycosylation Via Asparagine Cell Death Death Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Membrane Raft Polarization Regulation Of Calcium-transporting ATPase Activity Negative Regulation Of Receptor Catabolic Process Adrenergic Receptor Signaling Pathway Involved In Heart Process Protein N-linked Glycosylation Positive Regulation Of JNK Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Nerve Growth Factor Processing G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Membrane Raft Localization Dolichyl Diphosphate Biosynthetic Process Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Signal Transduction Negative Regulation Of Calcium Ion Import Negative Regulation Of Transforming Growth Factor Beta Production Ectodermal Cell Differentiation Regulation Of JNK Cascade Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Relaxation Of Cardiac Muscle Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Salivary Gland Cavitation Regulation Of Stress-activated MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of ATPase Activity Regulation Of Relaxation Of Muscle Vesicle Fusion With Golgi Apparatus Regulation Of Cardiac Muscle Cell Membrane Potential Post-translational Protein Modification Transport	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Trachea Gland Development Collateral Sprouting Axon Midline Choice Point Recognition Establishment Of Epithelial Cell Apical/basal Polarity Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Salivary Gland Cavitation Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Anatomical Structure Morphogenesis Neuron Remodeling Establishment Of Monopolar Cell Polarity Establishment Of Epithelial Cell Polarity Hair Follicle Placode Formation Cellular Copper Ion Homeostasis Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of NF-kappaB Import Into Nucleus Copper Ion Homeostasis Suckling Behavior Morphogenesis Of A Polarized Epithelium Cell Differentiation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Ectoderm Development Establishment Or Maintenance Of Apical/basal Cell Polarity Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Trachea Development Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Positive Regulation Of Transcription Factor Import Into Nucleus Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of NF-kappaB Import Into Nucleus Ionotropic Glutamate Receptor Signaling Pathway Salivary Gland Morphogenesis Regulation Of G2/M Transition Of Mitotic Cell Cycle Salivary Gland Development Regulation Of Cell Cycle G2/M Phase Transition Epithelium Development Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Cell Adhesion
Tagcloud ?		amplitudes asymmetry atypical comparison conductance contralateral depend discrepancy disinhibition electrodermal former frontal hemisphere idea left lesion motor neurophysiological phasic rejected right scl scls seem showing sweating tonic unrelated weakness
Tagcloud (Difference) ?		amplitudes asymmetry atypical comparison conductance contralateral depend discrepancy disinhibition electrodermal former frontal hemisphere idea left lesion motor neurophysiological phasic rejected right scl scls seem showing sweating tonic unrelated weakness
Tagcloud (Intersection) ?