CATSPERT and VPS52

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CATSPERT	VPS52
Description		catsper channel auxiliary subunit tau	VPS52 subunit of GARP complex
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane Motile Cilium CatSper Complex Cell Projection Sperm Principal Piece	GARP Complex Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Presynapse Postsynapse EARP Complex
	Molecular Function	Protein Binding	Protein Binding Syntaxin Binding
	Biological Process	Spermatogenesis Flagellated Sperm Motility Sperm Capacitation Vesicle-mediated Transport To The Plasma Membrane	Protein Targeting Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development Vesicle-mediated Cholesterol Transport
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)
Interacting Genes		62 interacting genes: ACOT11 ACTN3 ANKK1 AP2B1 BBS4 BRCA1 CARD9 CCDC172 CCDC57 CCDC85B CDR2 CHCHD3 CNOT11 CT55 DISC1 DNAJA3 FAM217B FHL2 GOLGA2 GPRASP3 GRAMD4 HAP1 HSF2BP HSPB8 IKZF3 JRK KIFC3 KRT13 KRT15 KRT31 KRT40 KRT75 LHX1 LHX3 LZTS2 MCM6 MCRS1 MEAF6 MEOX1 MIPOL1 MTUS2 NR5A1 NUTM1 PAX6 PIBF1 RNF8 SPATA2 TACC3 TCP10L TEX11 TFIP11 TLE5 TRAF1 TRAF2 TRIM23 TRIM54 TSSK3 VAC14 VIM VPS52 ZNF474 ZNRD2	101 interacting genes: AAMP AIRIM ARNT2 ATP6V1D BYSL C1orf216 CABP5 CACNA1A CATSPERT CCDC102B CCDC13 CCDC146 CCDC185 CCDC187 CCDC33 CCDC57 CCHCR1 CDC20B CDC5L CDK18 CEP19 CFAP206 CWF19L2 DCX DDX6 DNAJC11 DTNB EPM2AIP1 FAM110A FAM161A FAM161B FAM184A FAM50B GEM GFM2 GOLGA1 GORASP2 GPKOW HAUS1 HDAC4 HEATR1 HGS HOXB5 JAKMIP2 KANK2 KIAA1217 KIF5B KIF9 KIFC3 KLC3 KLHL42 LMO4 LNX1 MAGEL2 MAPK3 METTL13 MFAP1 MRPL1 MRPL11 NDC80 NFKBIB NOP2 NR2C2AP OTUD6A PIMREG PKN3 PPP1R18 PRKAA1 PRKAA2 RAB4A RAB4B RABEP2 RUNX1T1 SCNM1 SH2D4A SMARCE1 STX11 TAB2 TBC1D1 TBC1D22B TCEANC TCP11L1 TEAD4 THAP11 TPM3 TRAF4 TRAF6 TSSK3 TSTD2 TXLNB TXN2 USP2 VEZF1 VPS28 VPS53 WASHC3 WTAP ZC2HC1C ZMAT2 ZNF417 ZNF587
Entrez ID		151254	6293
HPRD ID		08687	09142
Ensembl ID		ENSG00000155754	ENSG00000223501
Uniprot IDs		A0A140VJE2 Q53TS8	A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytoskeleton Organization Identical Protein Binding Cytoskeleton Structural Constituent Of Skin Epidermis Protein Binding Centrosome Intermediate Filament Keratin Filament Microtubule-based Process Organelle Organization Cytoplasm Protein Localization To Centrosome Centriolar Satellite Cell Differentiation Regulation Of Programmed Cell Death Microtubule Cytoskeleton Organization Microtubule Organizing Center Organization Ureter Morphogenesis Developmental Process Ventral Spinal Cord Development Cellular Developmental Process Transcription Coregulator Binding Structural Molecule Activity Regulation Of Apoptotic Process Thioesterase Binding Epithelial Cell Differentiation Spinal Cord Association Neuron Differentiation Protein Localization To Cytoskeleton Centrosome Cycle Intermediate Filament Cytoskeleton Regulation Of Non-motile Cilium Assembly HMG Box Domain Binding Non-motile Cilium Assembly	Protein Binding Cytoskeleton Organelle Assembly Centrosome Microtubule Binding Microtubule-based Process Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Organelle Organization Organelle Disassembly Ciliary Basal Body Kinesin Complex Protein Localization To Lipid Droplet Protein Localization To Vacuole Microtubule Cytoskeleton Organization Protein Localization To Lysosome Negative Regulation Of Tubulin Deacetylation Negative Regulation Of Hepatocyte Apoptotic Process AMP-activated Protein Kinase Activity Insulin-responsive Compartment Centriole
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