CATSPERT and GRAMD4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CATSPERT	GRAMD4
Description		catsper channel auxiliary subunit tau	GRAM domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane Motile Cilium CatSper Complex Cell Projection Sperm Principal Piece	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Spermatogenesis Flagellated Sperm Motility Sperm Capacitation Vesicle-mediated Transport To The Plasma Membrane	Apoptotic Process Negative Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS			Urate levels in obese individuals ( 25811787)
Interacting Genes		62 interacting genes: ACOT11 ACTN3 ANKK1 AP2B1 BBS4 BRCA1 CARD9 CCDC172 CCDC57 CCDC85B CDR2 CHCHD3 CNOT11 CT55 DISC1 DNAJA3 FAM217B FHL2 GOLGA2 GPRASP3 GRAMD4 HAP1 HSF2BP HSPB8 IKZF3 JRK KIFC3 KRT13 KRT15 KRT31 KRT40 KRT75 LHX1 LHX3 LZTS2 MCM6 MCRS1 MEAF6 MEOX1 MIPOL1 MTUS2 NR5A1 NUTM1 PAX6 PIBF1 RNF8 SPATA2 TACC3 TCP10L TEX11 TFIP11 TLE5 TRAF1 TRAF2 TRIM23 TRIM54 TSSK3 VAC14 VIM VPS52 ZNF474 ZNRD2	13 interacting genes: APP CATSPERT CCDC146 EXOC8 FAM9B GADD45G MTMR9 NTAQ1 PLEKHF2 RBL2 SH2D4A SMARCD1 TACC2
Entrez ID		151254	23151
HPRD ID		08687	11107
Ensembl ID		ENSG00000155754	ENSG00000075240
Uniprot IDs		A0A140VJE2 Q53TS8	Q6IC98
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytoskeleton Organization Identical Protein Binding Cytoskeleton Structural Constituent Of Skin Epidermis Protein Binding Centrosome Intermediate Filament Keratin Filament Microtubule-based Process Organelle Organization Cytoplasm Protein Localization To Centrosome Centriolar Satellite Cell Differentiation Regulation Of Programmed Cell Death Microtubule Cytoskeleton Organization Microtubule Organizing Center Organization Ureter Morphogenesis Developmental Process Ventral Spinal Cord Development Cellular Developmental Process Transcription Coregulator Binding Structural Molecule Activity Regulation Of Apoptotic Process Thioesterase Binding Epithelial Cell Differentiation Spinal Cord Association Neuron Differentiation Protein Localization To Cytoskeleton Centrosome Cycle Intermediate Filament Cytoskeleton Regulation Of Non-motile Cilium Assembly HMG Box Domain Binding Non-motile Cilium Assembly
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