CATSPERT and SPATA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CATSPERT	SPATA2
Description		catsper channel auxiliary subunit tau	spermatogenesis associated 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane Motile Cilium CatSper Complex Cell Projection Sperm Principal Piece	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Signaling Receptor Complex Adaptor Activity Protein-containing Complex Binding Ubiquitin-specific Protease Binding
	Biological Process	Spermatogenesis Flagellated Sperm Motility Sperm Capacitation Vesicle-mediated Transport To The Plasma Membrane	Spermatogenesis Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Programmed Cell Death Regulation Of Inflammatory Response Regulation Of Necroptotic Process Necroptotic Process Protein K63-linked Deubiquitination Seminiferous Tubule Development Protein Linear Deubiquitination
Pathways			TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) Gut microbiota (beta diversity) ( 27723756) Psoriasis ( 18364390 20953189 25574825)
Interacting Genes		62 interacting genes: ACOT11 ACTN3 ANKK1 AP2B1 BBS4 BRCA1 CARD9 CCDC172 CCDC57 CCDC85B CDR2 CHCHD3 CNOT11 CT55 DISC1 DNAJA3 FAM217B FHL2 GOLGA2 GPRASP3 GRAMD4 HAP1 HSF2BP HSPB8 IKZF3 JRK KIFC3 KRT13 KRT15 KRT31 KRT40 KRT75 LHX1 LHX3 LZTS2 MCM6 MCRS1 MEAF6 MEOX1 MIPOL1 MTUS2 NR5A1 NUTM1 PAX6 PIBF1 RNF8 SPATA2 TACC3 TCP10L TEX11 TFIP11 TLE5 TRAF1 TRAF2 TRIM23 TRIM54 TSSK3 VAC14 VIM VPS52 ZNF474 ZNRD2	22 interacting genes: ANKRD11 APP ATP6V1H CATSPERT CCDC102B CEP72 DUT EFHC1 GOLGA2 GPANK1 KAT5 KIFC3 LENG1 MAD1L1 OTULIN PTPN6 TBC1D22B TNIP1 TRAF2 TRIM27 UBC ZNF835
Entrez ID		151254	9825
HPRD ID		08687	09636
Ensembl ID		ENSG00000155754	ENSG00000158480
Uniprot IDs		A0A140VJE2 Q53TS8	A8K0S9 B4DID4 Q9UM82
PDB IDs			5LJM 5LJN
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytoskeleton Organization Identical Protein Binding Cytoskeleton Structural Constituent Of Skin Epidermis Protein Binding Centrosome Intermediate Filament Keratin Filament Microtubule-based Process Organelle Organization Cytoplasm Protein Localization To Centrosome Centriolar Satellite Cell Differentiation Regulation Of Programmed Cell Death Microtubule Cytoskeleton Organization Microtubule Organizing Center Organization Ureter Morphogenesis Developmental Process Ventral Spinal Cord Development Cellular Developmental Process Transcription Coregulator Binding Structural Molecule Activity Regulation Of Apoptotic Process Thioesterase Binding Epithelial Cell Differentiation Spinal Cord Association Neuron Differentiation Protein Localization To Cytoskeleton Centrosome Cycle Intermediate Filament Cytoskeleton Regulation Of Non-motile Cilium Assembly HMG Box Domain Binding Non-motile Cilium Assembly	Microtubule-based Process Spindle Pole Pattern Recognition Receptor Signaling Pathway CD27 Signaling Pathway Positive Regulation Of Mitotic Sister Chromatid Segregation Innate Immune Response-activating Signaling Pathway Innate Immune Response Activation Of Innate Immune Response Regulation Of Metaphase Plate Congression Identical Protein Binding Regulation Of Innate Immune Response Defense Response To Symbiont Defense Response To Other Organism Positive Regulation Of Defense Response Cytoplasmic Pattern Recognition Receptor Signaling Pathway Attachment Of Mitotic Spindle Microtubules To Kinetochore Protein Serine/threonine Kinase Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Immune Response Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Defense Response Response To External Biotic Stimulus DUTP Catabolic Process DUTP Diphosphatase Activity Spindle Organization Positive Regulation Of Protein Modification Process Mitotic Spindle Regulation Of Autophagy Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Innate Immune Response Epididymis Development Immune Response-activating Signaling Pathway TORC2 Complex Disassembly Mitotic Spindle Pole Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Chromosome Segregation MAD1 Complex Histone H2AK5 Acetyltransferase Activity Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Microtubule-based Movement Regulation Of Cytokine-mediated Signaling Pathway Cytoskeleton Immune Response-regulating Signaling Pathway Regulation Of Inflammatory Response Activation Of Immune Response
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