SGOL2 and CDCA8

Number of citations of the paper that reports this interaction (PMID 20739936)
36

Data Source:
BioGRID (two hybrid)

		SGOL2	CDCA8
Gene Name		shugoshin-like 2 (S. pombe)	cell division cycle associated 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome Kinetochore Nucleoplasm Cytosol Mitotic Cohesin Complex	Chromosome, Centromeric Region Nucleus Nucleolus Spindle Cytosol Chromocenter Midbody Chromosome Passenger Complex Protein Complex Intercellular Bridge
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Cell Division Meiotic Sister Chromatid Cohesion, Centromeric	Mitotic Cell Cycle Mitotic Metaphase Plate Congression Chromosome Organization Cell Division
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CDCA8 PPP2CA PPP2R1A PPP2R1B	14 interactors: AURKB BIRC5 HIST2H3C HLA-DRB3 INCENP MAPKAPK5 NEK3 RANBP2 SGOL1 SGOL2 SUMO1 SUMO2 TTK UBE2I
Entrez ID		151246	55143
HPRD ID		11555	13017
Ensembl ID		ENSG00000163535	ENSG00000134690
Uniprot IDs		B7Z7S9 Q562F6	Q53HL2
PDB IDs			2KDD 2QFA 2RAW 2RAX
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Mitotic Nuclear Envelope Reassembly Nuclear Envelope Reassembly Negative Regulation Of JAK-STAT Cascade Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Inactivation Of MAPK Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Peptidyl-tyrosine Phosphorylation Nuclear Envelope Organization Negative Regulation Of MAP Kinase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of JAK-STAT Cascade Ceramide Metabolic Process Mitotic Cell Cycle Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Mitotic Cell Cycle Nucleus Organization Regulation Of DNA Replication Negative Regulation Of Protein Serine/threonine Kinase Activity Second-messenger-mediated Signaling Nuclear-transcribed MRNA Catabolic Process Negative Regulation Of Cell Growth Negative Regulation Of MAPK Cascade Sphingolipid Metabolic Process MRNA Catabolic Process Apoptotic Process Fibroblast Growth Factor Receptor Signaling Pathway Programmed Cell Death Peptidyl-serine Dephosphorylation Cell Cycle Process Cell Death Death RNA Catabolic Process Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Protein Kinase Activity Membrane Lipid Metabolic Process Chromosome Segregation Negative Regulation Of Kinase Activity Negative Regulation Of Growth Protein Dephosphorylation Cell Cycle Regulation Of MAP Kinase Activity Negative Regulation Of Transferase Activity Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Phosphorylation	Chromosome Segregation Mitotic Cell Cycle Cell Cycle Process Protein Sumoylation Mitotic Cell Cycle Process Cell Division Cell Cycle Mitotic Nuclear Division Organelle Organization Spindle Checkpoint Mitotic Spindle Organization Peptidyl-amino Acid Modification Peptidyl-lysine Modification Cellular Protein Modification Process Attachment Of Spindle Microtubules To Kinetochore Protein Modification By Small Protein Conjugation Cytokinesis Spindle Organization Mitotic Spindle Assembly Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Microtubule Cytoskeleton Organization Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Post-translational Protein Modification Negative Regulation Of Transcription, DNA-templated Cell Cycle Checkpoint Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Division Regulation Of Proteolysis Microtubule Anchoring Meiotic Sister Chromatid Cohesion, Centromeric Positive Regulation Of SUMO Transferase Activity Protein Phosphorylation Negative Regulation Of Gene Expression Nuclear Envelope Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Proteasomal Protein Catabolic Process Microtubule-based Process Meiotic Chromosome Segregation Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Spindle Assembly Protein Metabolic Process Regulation Of Type B Pancreatic Cell Proliferation Regulation Of Protein Catabolic Process Negative Regulation Of Binding Histone H3-S28 Phosphorylation
Tagcloud ?			allele aurkb birc5 consortium contribution cpc division european exon familial fifteen fixed genotyped incenp inherited investigates meta modest passenger pivotal rs1675126 rs2071214 snp snps spite sporadic synonymous top variability
Tagcloud (Difference) ?			allele aurkb birc5 consortium contribution cpc division european exon familial fifteen fixed genotyped incenp inherited investigates meta modest passenger pivotal rs1675126 rs2071214 snp snps spite sporadic synonymous top variability
Tagcloud (Intersection) ?