SGO2

Description		shugoshin 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Nucleus Nucleoplasm Chromosome Cytosol Nuclear Body Mitotic Cohesin Complex
	Molecular Function	Protein Binding
	Biological Process	Chromosome Segregation Meiotic Sister Chromatid Cohesion Cell Division Meiotic Cell Cycle
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: C2orf69
Interacting Genes		7 interacting genes: CDCA8 EXOSC8 PPP2CA PPP2R1A PPP2R1B SET SLAIN2
Entrez ID		151246
HPRD ID		11555
Ensembl ID		ENSG00000163535
Uniprot IDs		B7Z7S9 Q562F6
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Phosphatase Type 2A Complex RNA Surveillance Nuclear RNA Surveillance Protein Phosphatase Regulator Activity Meiotic Sister Chromatid Cohesion, Centromeric Microtubule Cytoskeleton Spindle Assembly Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Meiotic Sister Chromatid Cohesion INTAC Complex FAR/SIN/STRIPAK Complex Microtubule Cytoskeleton Organization RNA Polymerase II Transcription Initiation Surveillance Chromosome, Centromeric Region Spindle Organization Negative Regulation Of Hippo Signaling RNA Catabolic Process T Cell Homeostasis Chromosome Sister Chromatid Cohesion Regulation Of Hippo Signaling Transcription Elongation By RNA Polymerase II Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Membraneless Organelle Assembly DNA-templated Transcription Elongation Microtubule-based Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Lymphocyte Homeostasis Nucleobase-containing Compound Catabolic Process Regulation Of Microtubule Polymerization RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Meiotic Spindle Elongation Chromosome Organization Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Leukocyte Homeostasis Cytoskeleton Organization Protein Serine/threonine Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Regulation Of Meiotic Cell Cycle Process Involved In Oocyte Maturation Regulation Of Microtubule Polymerization Or Depolymerization U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Mitotic Cell Cycle Cytosol Chromosome Segregation Positive Regulation Of Apoptotic Signaling Pathway Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Mitotic Sister Chromatid Separation
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