CDCA8 and GAS2L3

Number of citations of the paper that reports this interaction (PubMedID 24571573)
0

Data Source:
BioGRID (pull down, pull down)

		CDCA8	GAS2L3
Description		cell division cycle associated 8	growth arrest specific 2 like 3
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Spindle Cytosol Cytoskeleton Chromocenter Microtubule Cytoskeleton Midbody Chromosome Passenger Complex Protein-containing Complex Intercellular Bridge Spindle Midzone	Cytoplasm Cytoskeleton Microtubule Actin Cytoskeleton Microtubule Cytoskeleton
	Molecular Function	Protein Binding	Actin Binding Protein Binding Microtubule Binding Actin Filament Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Mitotic Cytokinesis Mitotic Metaphase Chromosome Alignment Mitotic Spindle Midzone Assembly Chromosome Organization Cell Division Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Mitotic Spindle Assembly Positive Regulation Of Mitotic Sister Chromatid Separation Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Positive Regulation Of Mitotic Cytokinesis	Microtubule Cytoskeleton Organization Actin Cytoskeleton Organization Actin Crosslink Formation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Axial length ( 24144296) Eyebrow thickness ( 26926045)	Squamous cell carcinoma ( 23341777)
Interacting Genes		28 interacting genes: AURKB BIRC5 EMILIN1 FBXO17 GAS2L3 GYS1 H3C14 HLA-DRB3 HMBOX1 INCENP KMT2E MAPKAPK5 NEK3 NKAPD1 NTAQ1 PIAS2 PIH1D2 RANBP2 RPRD1B SENP3 SET SGO1 SGO2 SNAPC5 SPANXN2 TTK UBE2I ZNF277	7 interacting genes: AURKB BIRC5 CDCA8 CDK1 FNDC3B MFHAS1 TSR2
Entrez ID		55143	283431
HPRD ID		13017	13568
Ensembl ID		ENSG00000134690	ENSG00000139354
Uniprot IDs		Q53HL2	B3KTH9 G3V1N3 Q86XJ1
PDB IDs		2KDD 2QFA 2RAW 2RAX 6YIE 6YIF 6YIH 7U5V 8RUP 8RUQ
Enriched GO Terms of Interacting Partners?		Chromosome Segregation Chromosome Passenger Complex Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Kinetochore Mitotic Spindle Midzone Assembly Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Spindle Midzone Assembly Positive Regulation Of Mitotic Cytokinesis Regulation Of Metaphase Plate Congression Regulation Of Mitotic Cytokinesis Nuclear Body Repair Of Mitotic Kinetochore Microtubule Attachment Defect Regulation Of Mitotic Sister Chromatid Separation Positive Regulation Of Cell Cycle Checkpoint SUMO Transferase Activity Chromosome, Centromeric Region Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Mitotic Sister Chromatid Separation Cell Division Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Regulation Of Chromosome Separation Chromosome Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Chromosome Segregation SUMO Ligase Complex Mitotic Spindle Organization Positive Regulation Of Chromosome Separation Regulation Of Sister Chromatid Segregation Regulation Of Mitotic Nuclear Division Regulation Of Chromosome Organization Positive Regulation Of Cytokinesis Mitotic Spindle Assembly Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Chromosome Segregation Mitotic Cell Cycle Regulation Of Nuclear Division Protein Sumoylation Nucleoplasm Spindle Organization Mitotic Cytokinesis Chromocenter Regulation Of Mitotic Cell Cycle Phase Transition SUMO Ligase Activity Protein Localization To Kinetochore Meiotic Chromosome Segregation Nucleus Regulation Of Cytokinesis Condensed Chromosome, Centromeric Region	Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Metaphase Plate Congression Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Chromosome Segregation Chromosome Passenger Complex Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Mitotic Spindle Midzone Assembly Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Spindle Midzone Assembly Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Positive Regulation Of Cell Cycle Checkpoint Regulation Of Sister Chromatid Segregation Positive Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Microtubule Cytoskeleton Organization Involved In Mitosis Spindle Midzone Regulation Of Chromosome Segregation Positive Regulation Of Chromosome Separation Midbody Spindle Microtubule Positive Regulation Of Cytokinesis Mitotic Spindle Assembly Spindle Cell Cycle G2/M Phase Transition Regulation Of Chromosome Organization Regulation Of Mitotic Sister Chromatid Separation Positive Regulation Of Cell Cycle Process Mitotic Cytokinesis Regulation Of Chromosome Separation Regulation Of Cytokinesis Positive Regulation Of Cell Cycle Positive Regulation Of Cell Division Mitotic Spindle Organization Cytoskeleton-dependent Cytokinesis Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Mitotic Cell Cycle Phase Transition Spindle Assembly Positive Regulation Of Mitotic Sister Chromatid Segregation Chromocenter Regulation Of Mitotic Nuclear Division Protein Localization To Kinetochore Regulation Of Cell Cycle Phase Transition Microtubule Cytoskeleton Organization Cell Division Mitotic Cell Cycle Regulation Of Nuclear Division Regulation Of Mitotic Cell Cycle Spindle Organization
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