KANK2 and CCDC33

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KANK2	CCDC33
Gene Name		KN motif and ankyrin repeat domains 2	coiled-coil domain containing 33
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Apoptotic Process Negative Regulation Of Cell Proliferation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Programmed Cell Death Negative Regulation Of Vitamin D Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		HDL cholesterol ( 23505323)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		22 interactors: ABI3 AES CCDC33 CCDC36 CEP70 CSNK2A1 DYNLL1 EIF4E FHL2 GOLGA2 GPSM1 LMO1 LMO2 LMO4 MAGEB4 MOB1A NCOA1 NOS3 PSEN1 STAC TXLNA VPS52	91 interactors: ABCF3 ABLIM3 APP ARIH2 ARMC7 ARNT2 BCCIP BLK BLZF1 BYSL CALCOCO2 CCDC102B CCDC85B CCNH CDCA7L CDKN2B CENPP CHCHD3 DGCR6 DIP2A DVL2 EFEMP2 EHMT2 EMC2 EMD FAM124A FAM161A FXR2 GPATCH2L GRN HGS HNRNPF HNRNPK HOOK2 HOXA1 ING5 KANK2 KCTD19 KCTD9 KHDRBS3 KIFC3 KXD1 LDOC1 LMO2 LMO3 MAGED1 MAPK9 MDFI MIPOL1 MOS NAB2 NCK2 NDOR1 NECAB2 NINL OSGIN1 PID1 PIN1 PLSCR1 PNMA1 PNMA2 POLR1C PPP2R3C PRKAB2 PTGER3 PTK6 RAD54B RBMX RHOXF2 SCNM1 SMAD3 SPAG5 SPG21 SSSCA1 STK16 STX11 TGFB1 TMCC2 TRAF2 TRIM37 TRIM42 TSC22D4 TSGA10 TTC19 TUFT1 UBQLN4 USHBP1 VPS52 ZBTB8A ZGPAT ZNF572
Entrez ID		25959	80125
HPRD ID		12463	09959
Ensembl ID		ENSG00000197256	ENSG00000140481
Uniprot IDs		Q63ZY3	Q8N5R6
PDB IDs		4HBD
Enriched GO Terms of Interacting Partners?		System Development Organ Development Anatomical Structure Morphogenesis Multicellular Organismal Development Anatomical Structure Development Regulation Of Apoptotic Process Regulation Of Cell Death Tube Development Embryo Development Regulation Of Protein Binding Developmental Process Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Androgen Receptor Signaling Pathway Embryonic Organ Development Cellular Response To Extracellular Stimulus Gene Expression Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Cajal-Retzius Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose Beta-amyloid Formation Negative Regulation Of Protein Binding Thymus Development Macromolecule Biosynthetic Process Positive Regulation Of Apoptotic Process Regulation Of Binding Positive Regulation Of Programmed Cell Death Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Biosynthetic Process Cell Cycle Phase Transition Positive Regulation Of Cell Death Transcription, DNA-templated Wnt Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Cellular Protein Catabolic Process Biosynthetic Process RNA Biosynthetic Process Smooth Muscle Hyperplasia Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Embryonic Ectodermal Digestive Tract Development Rhythmic Process Mitotic Cell Cycle Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Atrial Cardiac Muscle Cell Development Regulation Of Cellular Response To Drug	Regulation Of Gene Expression Regulation Of Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Phosphorylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Protein Kinase Activity Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Transcription, DNA-templated Regulation Of Phosphorus Metabolic Process RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cell Proliferation Negative Regulation Of Phosphorylation Cellular Nitrogen Compound Metabolic Process Immune System Process Transcription From RNA Polymerase II Promoter Cell Cycle Process Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Cellular Process Regulation Of Cell Cycle Response To Organic Substance Organelle Organization Cellular Macromolecule Biosynthetic Process Positive Regulation Of Extracellular Matrix Assembly Positive Regulation Of Metabolic Process Negative Regulation Of Cell Proliferation Positive Regulation Of MAP Kinase Activity Nitrogen Compound Metabolic Process Negative Regulation Of Protein Phosphorylation
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