KANK2 and LMO1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KANK2	LMO1
Gene Name		KN motif and ankyrin repeat domains 2	LIM domain only 1 (rhombotin 1)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion	Nucleus
	Molecular Function	Protein Binding	Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Apoptotic Process Negative Regulation Of Cell Proliferation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Programmed Cell Death Negative Regulation Of Vitamin D Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		HDL cholesterol ( 23505323)	Alcohol consumption ( 23743675) Fasting glucose-related traits (interaction with BMI) ( 22581228) Neuroblastoma ( 22941191 21124317)
Protein-Protein Interactions		22 interactors: ABI3 AES CCDC33 CCDC36 CEP70 CSNK2A1 DYNLL1 EIF4E FHL2 GOLGA2 GPSM1 LMO1 LMO2 LMO4 MAGEB4 MOB1A NCOA1 NOS3 PSEN1 STAC TXLNA VPS52	38 interactors: ADAMTSL4 AES BCL11A BLZF1 CARD9 CDCA7L CDX4 CEP170P1 CEP44 ERBB2IP FAM154A FAM208B GABPB1 GATA3 GOLGA2 IKZF3 KANK2 KRT40 LDB1 LPXN LYL1 LZTS2 NHLH1 NUTM1 PHC2 PTPN3 RBBP8 REL SNTA1 SOX5 SPERT TAL1 TAL2 TCF4 TFIP11 TRIM27 ZBTB43 ZNF219
Entrez ID		25959	4004
HPRD ID		12463	01738
Ensembl ID		ENSG00000197256	ENSG00000166407
Uniprot IDs		Q63ZY3	P25800
PDB IDs		4HBD
Enriched GO Terms of Interacting Partners?		System Development Organ Development Anatomical Structure Morphogenesis Multicellular Organismal Development Anatomical Structure Development Regulation Of Apoptotic Process Regulation Of Cell Death Tube Development Embryo Development Regulation Of Protein Binding Developmental Process Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Androgen Receptor Signaling Pathway Embryonic Organ Development Cellular Response To Extracellular Stimulus Gene Expression Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Cajal-Retzius Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose Beta-amyloid Formation Negative Regulation Of Protein Binding Thymus Development Macromolecule Biosynthetic Process Positive Regulation Of Apoptotic Process Regulation Of Binding Positive Regulation Of Programmed Cell Death Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Biosynthetic Process Cell Cycle Phase Transition Positive Regulation Of Cell Death Transcription, DNA-templated Wnt Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Cellular Protein Catabolic Process Biosynthetic Process RNA Biosynthetic Process Smooth Muscle Hyperplasia Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Embryonic Ectodermal Digestive Tract Development Rhythmic Process Mitotic Cell Cycle Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Atrial Cardiac Muscle Cell Development Regulation Of Cellular Response To Drug	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Wnt Signaling Pathway Organ Development Positive Regulation Of Cellular Metabolic Process Interferon-gamma Secretion Multicellular Organismal Development Cellular Metabolic Process Anatomical Structure Development Developmental Process System Development Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Regulation Of Binding Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Cytokine Biosynthetic Process Definitive Hemopoiesis Embryo Development
Tagcloud ?			bhlh collaborates collaboration construct demonstrating dispensable dysregulation elements exerts helix inappropriately interfere interstitial juxtaposed lastly lymphoblastic mesoderm misexpressed oncogenesis product recapitulating scl sil situation supporting tcl5 transactivation translocations whereby
Tagcloud (Difference) ?			bhlh collaborates collaboration construct demonstrating dispensable dysregulation elements exerts helix inappropriately interfere interstitial juxtaposed lastly lymphoblastic mesoderm misexpressed oncogenesis product recapitulating scl sil situation supporting tcl5 transactivation translocations whereby
Tagcloud (Intersection) ?