KANK2 and TXLNA

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KANK2	TXLNA
Gene Name		KN motif and ankyrin repeat domains 2	taxilin alpha
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion	Extracellular Region Cytoplasm Membrane
	Molecular Function	Protein Binding	Cytokine Activity Protein Binding Syntaxin Binding High Molecular Weight B Cell Growth Factor Receptor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Apoptotic Process Negative Regulation Of Cell Proliferation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Programmed Cell Death Negative Regulation Of Vitamin D Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Exocytosis Cell Proliferation B Cell Activation
Pathways
Drugs
Diseases
GWAS		HDL cholesterol ( 23505323)
Protein-Protein Interactions		22 interactors: ABI3 AES CCDC33 CCDC36 CEP70 CSNK2A1 DYNLL1 EIF4E FHL2 GOLGA2 GPSM1 LMO1 LMO2 LMO4 MAGEB4 MOB1A NCOA1 NOS3 PSEN1 STAC TXLNA VPS52	53 interactors: AZI2 BRCA1 BTF3 BTF3L4 CCDC136 CCDC53 CCDC67 CCHCR1 CDR2 CEP44 CEP57L1 CEP63 DTNB EIF4ENIF1 GOLGA2 GORASP2 HAUS3 HYPK IKBKG KANK2 KRT13 KRT15 KRT20 KRT31 KRT38 KRT40 LCA5 MBIP MED4 MEOX1 MEOX2 NACA NDC80 NMI NSMCE2 NUP62 PPFIA1 RCOR3 RINT1 SMARCE1 SPERT STMN2 STX1A STX3 STX4 TBK1 TCL1A TFIP11 TNIP1 TP53BP2 TXLNB USHBP1 VPS52
Entrez ID		25959	200081
HPRD ID		12463	09408
Ensembl ID		ENSG00000197256	ENSG00000084652
Uniprot IDs		Q63ZY3	P40222
PDB IDs		4HBD
Enriched GO Terms of Interacting Partners?		System Development Organ Development Anatomical Structure Morphogenesis Multicellular Organismal Development Anatomical Structure Development Regulation Of Apoptotic Process Regulation Of Cell Death Tube Development Embryo Development Regulation Of Protein Binding Developmental Process Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Androgen Receptor Signaling Pathway Embryonic Organ Development Cellular Response To Extracellular Stimulus Gene Expression Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Cajal-Retzius Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose Beta-amyloid Formation Negative Regulation Of Protein Binding Thymus Development Macromolecule Biosynthetic Process Positive Regulation Of Apoptotic Process Regulation Of Binding Positive Regulation Of Programmed Cell Death Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Biosynthetic Process Cell Cycle Phase Transition Positive Regulation Of Cell Death Transcription, DNA-templated Wnt Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Cellular Protein Catabolic Process Biosynthetic Process RNA Biosynthetic Process Smooth Muscle Hyperplasia Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Embryonic Ectodermal Digestive Tract Development Rhythmic Process Mitotic Cell Cycle Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Atrial Cardiac Muscle Cell Development Regulation Of Cellular Response To Drug	Synaptic Vesicle Fusion To Presynaptic Membrane Dendritic Cell Proliferation Organelle Organization Protein Localization Cell Cycle Protein Transport Establishment Of Protein Localization Mitotic Cell Cycle Neurotransmitter Secretion Somite Specification Positive Regulation Of Protein Localization To Cell Surface Regulation Of Neurotransmitter Levels Vesicle Fusion Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Exocytosis I-kappaB Kinase/NF-kappaB Signaling Neurotransmitter Transport Establishment Of Organelle Localization Microtubule-based Process Type I Interferon Production Developmental Process Organelle Fusion Centriole Assembly Positive Regulation Of Transcription, DNA-templated Vesicle Docking Establishment Of Vesicle Localization Establishment Of Localization In Cell Segment Specification Interferon-gamma Production Vesicle Localization Cellular Localization Centrosome Organization Membrane Docking Regulation Of Protein Localization To Cell Surface Regulation Of I-kappaB Kinase/NF-kappaB Signaling Organelle Localization Microtubule Cytoskeleton Organization Microtubule Organizing Center Organization Glutamate Secretion Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Toll-like Receptor Signaling Pathway Synaptic Vesicle Transport Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Synaptic Transmission Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Spindle Organization Membrane Fusion Pattern Recognition Receptor Signaling Pathway
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