SIMC1

Description		SUMO interacting motifs containing 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm PML Body Sarcomere
	Molecular Function	Protein Binding Peptidase Inhibitor Activity SUMO Polymer Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: CSNK2B DNAJB11 PLK1 SUMO2 TUBA4A YWHAG YWHAZ
Entrez ID		375484
HPRD ID		13486
Ensembl ID		ENSG00000170085
Uniprot IDs		B4DRM7 Q8NDZ2
PDB IDs		7T5P
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Modification Process Protein Domain Specific Binding Regulation Of Proteasomal Protein Catabolic Process Protein Metabolic Process Hippocampal Mossy Fiber To CA3 Synapse Protein Sequestering Activity Cellular Response To Glucose Starvation Phosphorylation Protein Phosphorylation Regulation Of Protein Catabolic Process Regulation Of Proteolysis Regulation Of Protein Stability Negative Regulation Of TORC1 Signaling TORC1 Signaling Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process TOR Signaling Protein Kinase Binding Negative Regulation Of TOR Signaling PML Body Synaptonemal Complex Disassembly Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Golgi Inheritance Regulation Of TORC1 Signaling Synaptic Target Recognition Positive Regulation Of Proteasomal Protein Catabolic Process Golgi Organization Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Kinase C Inhibitor Activity Mitotic Cell Cycle Regulation Of TOR Signaling Regulation Of Protein Metabolic Process Regulation Of Protein Localization To Nucleus Release From Viral Latency Homologous Chromosome Segregation Female Meiosis Chromosome Segregation Protein Modification By Small Protein Conjugation Golgi Reassembly Positive Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Viral Life Cycle Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Cellular Response To Starvation Vesicle Phosphoserine Residue Binding Macromolecule Metabolic Process Positive Regulation Of Proteolysis
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