ADPRH and TFCP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ADPRH	TFCP2
Description		ADP-ribosylarginine hydrolase	transcription factor CP2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	Magnesium Ion Binding ADP-ribosylarginine Hydrolase Activity Protein Binding Hydrolase Activity Potassium Ion Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Modification Process Protein De-ADP-ribosylation	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Vitiligo ( 27723757)
Interacting Genes		5 interacting genes: ACD SPSB1 SRPK1 SRPK2 TFCP2	73 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 FXR2 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I YJU2 YY1 ZCCHC10 ZCCHC12
Entrez ID		141	7024
HPRD ID		04359	01790
Ensembl ID		ENSG00000144843	ENSG00000135457
Uniprot IDs		A8K6X2 B4E341 P54922	Q12800
PDB IDs		3HFW 6G28 6G2A 6IUX
Enriched GO Terms of Interacting Partners?		Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Positive Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Regulation Of Viral Life Cycle MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Chromosome Regulation Of Viral Process Nucleic Acid Metabolic Process Regulation Of RNA Splicing Nuclear Speck Organization Telomere Assembly Protein-RNA Complex Assembly Magnesium Ion Binding Macromolecule Metabolic Process Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Regulation Of Establishment Of Protein Localization To Telomere Protection From Non-homologous End Joining At Telomere Shelterin Complex Establishment Of Protein Localization To Telomere Nucleobase-containing Compound Metabolic Process Chromatin R-loop Processing Nuclear Telomere Cap Complex Protein Localization To Chromosome, Telomeric Region Regulation Of MRNA Metabolic Process Telomere Capping Protein Serine Kinase Activity Protein Phosphorylation Telomere Maintenance In Response To DNA Damage RNA Splicing Phosphorylation RNA Metabolic Process Urogenital System Development Protein Serine/threonine Kinase Activity Nuclear Body Organization Nuclear Speck Sperm DNA Condensation MRNA Processing Transcription Factor Binding Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Telomerase Holoenzyme Complex DNA Polymerase Binding Protein Modification Process	Nucleus Sin3-type Complex Protein Binding Nucleoplasm DNA Damage Response MAP Kinase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation RING-like Zinc Finger Domain Binding Macromolecule Metabolic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Stress-activated MAPK Cascade Chromatin Binding Chromatin Organization Stress-activated Protein Kinase Signaling Cascade Hair Follicle Placode Formation Negative Regulation Of Stem Cell Population Maintenance PcG Protein Complex Small Protein Activating Enzyme Binding Postsynaptic Cytosol Cellular Response To Stress Enzyme Binding Cellular Response To Dopamine Response To Dopamine Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Self Proteolysis Fibroblast Proliferation Histone Deacetylase Complex Histone Deacetylase Activity, Hydrolytic Mechanism Substrate-dependent Cell Migration, Cell Extension Negative Regulation Of Gene Expression, Epigenetic
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