WFDC3 and LCE1F

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		WFDC3	LCE1F
Description		WAP four-disulfide core domain 3	late cornified envelope 1F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity	Protein Binding Identical Protein Binding
	Biological Process	Antibacterial Humoral Response Innate Immune Response	Epidermis Development Keratinization
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS			Asthma ( 31619474)
Interacting Genes		2 interacting genes: GET3 LCE1F	90 interacting genes: ADAMTSL4 ALPP CATSPER1 CHIC2 CHRD CRCT1 CREB5 CYP21A2 CYSRT1 FBLN1 HOXA1 IL34 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE4A LCE5A MACO1 MDFI NBPF19 NECTIN2 NOTCH2NLA NTAQ1 NUFIP2 OIT3 OTX1 PCSK5 PLA2G10 POU4F2 PSMB1 RAD54L2 RGS17 RGS20 RNF4 SLC39A7 SMCP SPRY1 SPRY2 SPRY3 TGFB1 TRIM42 UBE2I VASN VWC2 WFDC3
Entrez ID		140686	353137
HPRD ID		15676	13970
Ensembl ID		ENSG00000124116	ENSG00000240386
Uniprot IDs		Q8IUB2	Q5T754
PDB IDs
Enriched GO Terms of Interacting Partners?		GET Complex Membrane Insertase Activity Protein Insertion Into ER Membrane Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Endogenous Antigen Tail-anchored Membrane Protein Insertion Into ER Membrane Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Peptide Antigen Protein Insertion Into Membrane Keratinization Antigen Processing And Presentation	Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Protein Binding Identical Protein Binding Branch Elongation Of An Epithelium Axis Elongation Cytosol Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of Ras Protein Signal Transduction Microtubule End Negative Regulation Of Cellular Response To Growth Factor Stimulus Bud Elongation Involved In Lung Branching Interstitial Matrix
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