TMEM139 and CXCL16

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM139	CXCL16
Description		transmembrane protein 139	C-X-C motif chemokine ligand 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Extracellular Region Extracellular Space Plasma Membrane Membrane
	Molecular Function	Protein Binding	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Cytokine Activity Chemokine Activity
	Biological Process		Receptor-mediated Endocytosis Chemotaxis Signal Transduction T Cell Chemotaxis Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Response To Cytokine Response To Type II Interferon Response To Tumor Necrosis Factor Lymphocyte Chemotaxis
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Blood protein levels in cardiovascular risk ( 28369058)
Interacting Genes		41 interacting genes: ABHD16A AGTRAP APOL2 ATP6V0C BCL2L2 CD151 CDS2 CLN6 CMTM5 CTSA CXCL16 CYB5B FAXDC2 KCNK1 MALL MARCHF5 MIP NAPB NEDD4 NINJ2 NKG7 NSG1 PLPP4 PMP22 SEC22B SFTPC SLC30A8 SLC35A1 SMCO4 SMURF2 TMEM107 TMEM120B TMEM19 TMEM60 TRAF3IP3 UBIAD1 UPK1B VAMP5 YAP1 YIF1A ZFPL1	66 interacting genes: ADAMTSL4 APP AQP2 AQP6 AQP9 ARL13B ATP6V0E1 BIK CARD10 CCDC70 CD53 CERS4 CLDN7 CREB3L1 CXCR6 CYSRT1 FAM209A FFAR2 FKBP7 FNDC9 GJA8 GORAB GPR42 GPX8 HHATL HOXA1 KASH5 KIR2DL3 KRT31 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP5-9 LHFPL5 LMNA MDFI MFF MTUS2 MUC1 NBPF19 NEMP1 NOTCH2NLA PEX12 SAR1A SLC10A6 SLC16A2 SLC18A1 SLC39A1 SNCA SPN SSMEM1 STX1A TGM1 TLCD4 TMEM139 TMEM14B TMEM237 TMEM239 TMEM35A TMX2 TSPAN12
Entrez ID		135932	58191
HPRD ID		08298	16103
Ensembl ID		ENSG00000178826	ENSG00000161921
Uniprot IDs		Q8IV31	Q9H2A7
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Golgi Membrane	Intermediate Filament Keratin Filament Membrane Water Channel Activity Identical Protein Binding Cellular Response To Copper Ion Water Transport
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