CXCL16 and CXCR6

Number of citations of the paper that reports this interaction (PMID 11017100)
93

Data Source:
HPRD (in vitro, in vivo)

		CXCL16	CXCR6
Gene Name		chemokine (C-X-C motif) ligand 16	chemokine (C-X-C motif) receptor 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Low-density Lipoprotein Receptor Activity Scavenger Receptor Activity Chemokine Activity	G-protein Coupled Receptor Activity Coreceptor Activity C-X-C Chemokine Receptor Activity
	Biological Process	Receptor-mediated Endocytosis Chemotaxis T Cell Chemotaxis Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Response To Cytokine Response To Interferon-gamma Response To Tumor Necrosis Factor Cellular Response To Lipopolysaccharide	Chemotaxis Inflammatory Response G-protein Coupled Receptor Signaling Pathway Viral Genome Replication Chemokine-mediated Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ADAMTSL4 APP CCDC155 CXCR6 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 MDFI MTUS2 NOTCH2NL TMEM239	1 interactors: CXCL16
Entrez ID		58191	10663
HPRD ID		16103	05520
Ensembl ID		ENSG00000161921	ENSG00000172215
Uniprot IDs		Q9H2A7	A0N0N3 O00574
PDB IDs
Enriched GO Terms of Interacting Partners?			T Cell Chemotaxis Lymphocyte Chemotaxis T Cell Migration Lymphocyte Migration Leukocyte Chemotaxis Positive Regulation Of Cell Growth Response To Tumor Necrosis Factor Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Cell Chemotaxis Response To Interferon-gamma Positive Regulation Of Growth Leukocyte Migration Response To Lipopolysaccharide Positive Regulation Of Cell Migration Response To Molecule Of Bacterial Origin Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Regulation Of Cell Growth Positive Regulation Of Locomotion Receptor-mediated Endocytosis Cellular Response To Lipid
Tagcloud ?		aaa aaas adventitial aneurysms aorta arteries atherosclerosis atherothrombosis atherothrombotic ccl19 ccl20 ccl21 chemokine chemokines chemotaxis conditioned contributors converted cryosections evolutive immunofluorescence medium qpcr sma smcs tertiary tlos trigger	apposed attack borrelia burgdorferi caught cd1d disk dissemination encompass explains extravascular fail glycolipids granzyme homing inkt intravital invariant joint joints killer lyme microbe microbes multichannel patrolling penetrance spinning vasculature
Tagcloud (Difference) ?		aaa aaas adventitial aneurysms aorta arteries atherosclerosis atherothrombosis atherothrombotic ccl19 ccl20 ccl21 chemokine chemokines chemotaxis conditioned contributors converted cryosections evolutive immunofluorescence medium qpcr sma smcs tertiary tlos trigger	apposed attack borrelia burgdorferi caught cd1d disk dissemination encompass explains extravascular fail glycolipids granzyme homing inkt intravital invariant joint joints killer lyme microbe microbes multichannel patrolling penetrance spinning vasculature
Tagcloud (Intersection) ?