CXCL16 and TMEM35A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CXCL16	TMEM35A
Description		C-X-C motif chemokine ligand 16	transmembrane protein 35A
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane	Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Cytokine Activity Chemokine Activity	Protein Binding Acetylcholine Receptor Regulator Activity
	Biological Process	Receptor-mediated Endocytosis Chemotaxis Signal Transduction T Cell Chemotaxis Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Response To Cytokine Response To Type II Interferon Response To Tumor Necrosis Factor Lymphocyte Chemotaxis	Chaperone-mediated Protein Complex Assembly Positive Regulation Of Protein Localization To Cell Surface
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Blood protein levels in cardiovascular risk ( 28369058)
Interacting Genes		66 interacting genes: ADAMTSL4 APP AQP2 AQP6 AQP9 ARL13B ATP6V0E1 BIK CARD10 CCDC70 CD53 CERS4 CLDN7 CREB3L1 CXCR6 CYSRT1 FAM209A FFAR2 FKBP7 FNDC9 GJA8 GORAB GPR42 GPX8 HHATL HOXA1 KASH5 KIR2DL3 KRT31 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP5-9 LHFPL5 LMNA MDFI MFF MTUS2 MUC1 NBPF19 NEMP1 NOTCH2NLA PEX12 SAR1A SLC10A6 SLC16A2 SLC18A1 SLC39A1 SNCA SPN SSMEM1 STX1A TGM1 TLCD4 TMEM139 TMEM14B TMEM237 TMEM239 TMEM35A TMX2 TSPAN12	32 interacting genes: ADIPOQ APP BET1 C16orf92 CMTM5 COX20 CTSA CXCL16 CYB5B EHHADH FXYD6 GIMAP1 GOSR2 LNPEP MGLL ORMDL1 RTP2 RUSF1 THBD TMEM106C TMEM120A TMEM14C TMEM201 TMEM222 TMEM229B TMEM243 TMEM42 TRIM55 TRIM63 VAMP1 VAMP3 VAPA
Entrez ID		58191	59353
HPRD ID		16103	06523
Ensembl ID		ENSG00000161921	ENSG00000126950
Uniprot IDs		Q9H2A7	Q53FP2
PDB IDs			9H9E
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Membrane Water Channel Activity Identical Protein Binding Cellular Response To Copper Ion Water Transport	Membrane Membrane Fusion SNAP Receptor Activity SNARE Complex Vesicle Fusion Organelle Membrane Fusion Organelle Fusion Membrane Organization Sphingomyelin Biosynthetic Process SNARE Complex Assembly Cellular Localization Endoplasmic Reticulum Vesicle Organization Positive Regulation Of CAMP/PKA Signal Transduction Response To CAMP Endoplasmic Reticulum Membrane Sphingomyelin Metabolic Process
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