CXCL16 and NEMP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CXCL16	NEMP1
Description		C-X-C motif chemokine ligand 16	nuclear envelope integral membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane	Nucleus Nuclear Envelope Nuclear Inner Membrane Membrane
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Cytokine Activity Chemokine Activity	Protein Binding
	Biological Process	Receptor-mediated Endocytosis Chemotaxis Signal Transduction T Cell Chemotaxis Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Response To Cytokine Response To Type II Interferon Response To Tumor Necrosis Factor Lymphocyte Chemotaxis	Erythrocyte Enucleation Erythrocyte Maturation Nuclear Membrane Organization
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Blood protein levels in cardiovascular risk ( 28369058)	Asthma ( 31959851)
Interacting Genes		66 interacting genes: ADAMTSL4 APP AQP2 AQP6 AQP9 ARL13B ATP6V0E1 BIK CARD10 CCDC70 CD53 CERS4 CLDN7 CREB3L1 CXCR6 CYSRT1 FAM209A FFAR2 FKBP7 FNDC9 GJA8 GORAB GPR42 GPX8 HHATL HOXA1 KASH5 KIR2DL3 KRT31 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP5-9 LHFPL5 LMNA MDFI MFF MTUS2 MUC1 NBPF19 NEMP1 NOTCH2NLA PEX12 SAR1A SLC10A6 SLC16A2 SLC18A1 SLC39A1 SNCA SPN SSMEM1 STX1A TGM1 TLCD4 TMEM139 TMEM14B TMEM237 TMEM239 TMEM35A TMX2 TSPAN12	31 interacting genes: ADIPOQ AQP10 ASGR1 BRICD5 C3orf52 C5 CD81 CLEC7A CLRN2 CNIH3 COL4A5 CXCL16 CXCL9 FAXDC2 GPR108 GUCA2A INSIG2 PNLIPRP1 RTP2 SCARF1 SERP2 STX12 TMEM14A TMEM229B TMEM42 TMEM86B TMEM97 TMUB2 TSPAN33 UPK1B VAMP3
Entrez ID		58191	23306
HPRD ID		16103	13793
Ensembl ID		ENSG00000161921	ENSG00000166881
Uniprot IDs		Q9H2A7	O14524
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Membrane Water Channel Activity Identical Protein Binding Cellular Response To Copper Ion Water Transport	Membrane Protein Localization To Cell Periphery Localization Within Membrane Chemokine Activity Tetraspanin-enriched Microdomain Receptor-mediated Endocytosis Positive Regulation Of Chemokine Production Protein Localization To Membrane Positive Regulation Of Monocyte Chemotactic Protein-1 Production Oxysterol Binding Protein Localization To Plasma Membrane
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