SLC31A2 and RAMP3

Number of citations of the paper that reports this interaction (PMID 14722252)
7

Data Source:
BioGRID (pull down)

		SLC31A2	RAMP3
Gene Name		solute carrier family 31 (copper transporter), member 2	receptor (G protein-coupled) activity modifying protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Late Endosome Integral Component Of Plasma Membrane Recycling Endosome	Intracellular Lysosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex
	Molecular Function	Copper Ion Transmembrane Transporter Activity	Receptor Activity Protein Binding Protein Transporter Activity Coreceptor Activity
	Biological Process	Copper Ion Transport Cellular Copper Ion Homeostasis Copper Ion Transmembrane Transport Regulation Of Copper Ion Transmembrane Transport	Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Protein Transport Receptor Internalization Negative Regulation Of Transcription, DNA-templated Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Calcitonin-like ligand receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)
Drugs			Pramlintide
Diseases
GWAS
Protein-Protein Interactions		4 interactors: RAMP1 RAMP2 RAMP3 VKORC1	10 interactors: CALCR CALCRL HSPB3 KRTAP10-3 KRTAP5-9 NOTCH2NL NSF PDCD6IP SLC31A2 VIPR1
Entrez ID		1318	10268
HPRD ID		04365	05517
Ensembl ID		ENSG00000136867	ENSG00000122679
Uniprot IDs		O15432 Q53X94	A4D2L1 O60896
PDB IDs
Enriched GO Terms of Interacting Partners?		Receptor Internalization Receptor Metabolic Process Protein Localization To Plasma Membrane Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Plasma Membrane Organization Calcium Ion Transport Receptor-mediated Endocytosis Protein Localization To Membrane Endomembrane System Organization Positive Regulation Of CAMP Biosynthetic Process Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Endocytosis Regulation Of CAMP Metabolic Process Response To Estradiol Metal Ion Transport Membrane Organization Intracellular Protein Transport G-protein Coupled Receptor Signaling Pathway Response To Estrogen Basement Membrane Assembly Cation Transport Positive Regulation Of Protein Glycosylation G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Vitamin K Metabolic Process Angiogenesis Vascular Smooth Muscle Cell Development Ion Transport Regulation Of Protein Glycosylation Positive Regulation Of Vasculogenesis Blood Vessel Morphogenesis Negative Regulation Of Vascular Permeability Protein Localization Peptidyl-glutamic Acid Carboxylation Establishment Of Localization In Cell Response To Steroid Hormone Positive Regulation Of Glycoprotein Biosynthetic Process Regulation Of Vasculogenesis Positive Regulation Of Glycoprotein Metabolic Process Blood Vessel Development Positive Regulation Of Receptor Recycling Vascular Smooth Muscle Cell Differentiation Vasculature Development Basement Membrane Organization	G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Receptor Internalization Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of CAMP Biosynthetic Process Positive Regulation Of CAMP Metabolic Process Regulation Of Copper Ion Transmembrane Transport Cellular Response To Sucrose Stimulus Receptor Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Golgi Vesicle Docking Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Protein Localization To Plasma Membrane Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Exocytosis Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Extracellular Vesicular Exosome Assembly Viral Budding Via Host ESCRT Complex Plasma Membrane Organization Metal Ion Transport Membrane Organization Viral Budding Protein Localization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Copper Ion Transmembrane Transport Response To Sucrose Positive Regulation Of Receptor Recycling Cellular Copper Ion Homeostasis Cell Separation After Cytokinesis Plasma Membrane Fusion Receptor-mediated Endocytosis G-protein Coupled Receptor Signaling Pathway Protein Localization To Membrane Cation Transport Regulation Of Vesicle-mediated Transport CAMP Biosynthetic Process Copper Ion Homeostasis Virion Assembly Golgi To Plasma Membrane Protein Transport Positive Regulation Of Organelle Assembly Cellular Metal Ion Homeostasis Copper Ion Transport Endomembrane System Organization Regulation Of Receptor Recycling Cellular Cation Homeostasis
Tagcloud ?			acidic amylin calcitonin calcr causally deltan glycolysis iapp implement interplay isoforms lymphomas manipulating p63 p73 pramlintide reactivation reprogramming resemble suppressive ta tap63 tap73 therapeutically thymic tp53 tp63 tp73 tumours
Tagcloud (Difference) ?			acidic amylin calcitonin calcr causally deltan glycolysis iapp implement interplay isoforms lymphomas manipulating p63 p73 pramlintide reactivation reprogramming resemble suppressive ta tap63 tap73 therapeutically thymic tp53 tp63 tp73 tumours
Tagcloud (Intersection) ?