CIMIP6 and SH3BP4

Number of citations of the paper that reports this interaction (PubMedID 18654987)
0

Data Source:
BioGRID (two hybrid)

		CIMIP6	SH3BP4
Description		ciliary microtubule inner protein 6	SH3 domain binding protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Cell Projection	Nucleus Cytoplasm Clathrin-coated Pit Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function		GDP-dissociation Inhibitor Activity Protein Binding Small GTPase Binding Identical Protein Binding
	Biological Process		Endocytosis Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways			Amino acids regulate mTORC1
Drugs
Diseases
GWAS			Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 34099189) Schizophrenia x sex interaction ( 34099189) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		3 interacting genes: FCHSD2 HSPB1 SH3BP4	23 interacting genes: CCT3 CEP78 CFTR CIMIP6 CIZ1 DNAJA4 EPS15 FKBP4 GAPDHS GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 SNCA TCP1 TTC1 TXNL1 YWHAG ZBTB37
Entrez ID		129852	23677
HPRD ID		13446	09285
Ensembl ID		ENSG00000177994	ENSG00000130147
Uniprot IDs		Q8N5S3	Q9P0V3
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Protein Localization Clathrin-coated Pit Unfolded Protein Binding Negative Regulation Of Protein Kinase C Signaling Stereocilium Shaft Protein Kinase C Inhibitor Activity Amino Acid Import Protein Transport Regulation Of Protein Kinase C Signaling Establishment Of Protein Localization Protein Transport Along Microtubule Anterograde Axonal Protein Transport Contractile Muscle Fiber Regulation Of Autophagy Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Protein Exit From Endoplasmic Reticulum Positive Regulation Of Endothelial Cell Chemotaxis GDP-dissociation Inhibitor Activity Negative Regulation Of GTPase Activity Endocytosis Retrograde Protein Transport, ER To Cytosol Regulation Of Protein Exit From Endoplasmic Reticulum Intracellular Protein Transport Endoplasmic Reticulum Quality Control Compartment Protein Refolding Phosphatidylinositol-3,4-bisphosphate Binding Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Protein Folding Unfolded Protein Binding ATP-dependent Protein Folding Chaperone Cytosol Protein Folding Chaperone Positive Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Protein Localization To Cajal Body Zona Pellucida Receptor Complex Chaperonin-containing T-complex Heat Shock Protein Binding Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Receptor Recycling Negative Regulation Of Microtubule Polymerization Protein-folding Chaperone Binding Positive Regulation Of Telomere Maintenance Via Telomerase Regulation Of Receptor Recycling Positive Regulation Of DNA Metabolic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Refolding Regulation Of Protein Localization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Steroid Hormone Receptor Complex Assembly Negative Regulation Of Protein-containing Complex Assembly Phosphoprotein Binding Regulation Of Protein Folding In Endoplasmic Reticulum Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Binding Of Sperm To Zona Pellucida Sperm-egg Recognition H4/H2A Histone Acetyltransferase Complex ATP Hydrolysis Activity Negative Regulation Of Microtubule Polymerization Or Depolymerization Tau Protein Binding Maintenance Of Protein Localization In Organelle Regulation Of Protein Stability Protein Sequestering Activity Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Biosynthetic Process
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