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MBD3L2 and MTA2
Number of citations of the paper that reports this interaction (PMID
15701600
)
9
Data Source:
BioGRID
(pull down)
MBD3L2
MTA2
Gene Name
methyl-CpG binding domain protein 3-like 2
metastasis associated 1 family, member 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Histone Deacetylase Complex
Nuclear Chromatin
Nucleoplasm
Transcription Factor Complex
Membrane
NuRD Complex
Protein Complex
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding
Transcription Factor Binding Transcription Factor Activity
RNA Polymerase II Transcription Factor Binding
RNA Polymerase II Repressing Transcription Factor Binding
Sequence-specific DNA Binding Transcription Factor Activity
Histone Deacetylase Activity
Protein Binding
Zinc Ion Binding
Nucleosomal DNA Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
DNA Methylation
Chromatin Organization
Chromatin Assembly Or Disassembly
Histone Deacetylation
ATP-dependent Chromatin Remodeling
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Chromatin modifying enzymes
Chromatin organization
HDACs deacetylate histones
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
CHD4
HDAC1
HDAC2
MBD2
MBD3
MTA1
MTA2
POLD3
RBBP4
RBBP7
21 interactors:
APPL1
APPL2
BCL11B
ESR1
FKBP3
HDAC2
HIST3H3
HNRNPD
MBD3
MBD3L2
MED30
NACC2
RBBP4
RBBP7
SATB1
SATB2
SPEN
TP53
TSC22D3
UBE3C
YY1
Entrez ID
125997
9219
HPRD ID
12139
07233
Ensembl ID
ENSG00000230522
ENSG00000149480
Uniprot IDs
Q8NHZ7
O94776
PDB IDs
Enriched GO Terms of Interacting Partners
?
ATP-dependent Chromatin Remodeling
Chromatin Remodeling
Regulation Of Gene Expression, Epigenetic
Chromosome Organization
Negative Regulation Of Gene Expression, Epigenetic
Chromatin Organization
Chromatin Modification
Organelle Organization
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Cellular Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Histone Deacetylation
Negative Regulation Of Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Protein Deacetylation
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Circadian Regulation Of Gene Expression
Fungiform Papilla Formation
Negative Regulation Of Cellular Metabolic Process
RNA Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Fungiform Papilla Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Receptor Biosynthetic Process
Gene Expression
Fungiform Papilla Development
Eyelid Development In Camera-type Eye
Hair Follicle Placode Formation
Histone Modification
Tongue Morphogenesis
Regulation Of Receptor Biosynthetic Process
Histone H4 Deacetylation
Chromatin Assembly Or Disassembly
DNA Metabolic Process
Circadian Rhythm
Negative Regulation Of Gene Expression
Chromosome Organization
Chromatin Remodeling
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Chromatin Organization
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
RNA Metabolic Process
Chromatin Modification
Regulation Of Nitrogen Compound Metabolic Process
Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
ATP-dependent Chromatin Remodeling
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Gene Expression, Epigenetic
Nitrogen Compound Metabolic Process
Positive Regulation Of Gene Expression
Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Organelle Organization
Positive Regulation Of Macromolecule Biosynthetic Process
Cell Proliferation
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Gene Expression, Epigenetic
Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain
Rhythmic Process
Regulation Of Apoptotic Process
Forebrain Neuron Fate Commitment
Cellular Metabolic Process
Regulation Of Cell Death
DNA Metabolic Process
Negative Regulation Of Cell Proliferation
Chromatin Assembly
Tagcloud
?
ag
ag1478
blocking
combat
combinatorial
dosage
egfr
exerts
fasn
greatly
hsp90
ideal
iialpha
iressa
isotope
labeling
lc
mechanistically
oncogenes
phosphatidylinositol
pi3k
pi4kiialpha
prdx2
presents
proteomic
silac
strengthened
ultimately
xenograft
Tagcloud (Difference)
?
ag
ag1478
blocking
combat
combinatorial
dosage
egfr
exerts
fasn
greatly
hsp90
ideal
iialpha
iressa
isotope
labeling
lc
mechanistically
oncogenes
phosphatidylinositol
pi3k
pi4kiialpha
prdx2
presents
proteomic
silac
strengthened
ultimately
xenograft
Tagcloud (Intersection)
?