MBD3L2 and RBBP7

Number of citations of the paper that reports this interaction (PMID 15701600)
9

Data Source:
BioGRID (pull down)

		MBD3L2	RBBP7
Gene Name		methyl-CpG binding domain protein 3-like 2	retinoblastoma binding protein 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm NuRD Complex ESC/E(Z) Complex
	Molecular Function		RNA Binding Protein Binding
	Biological Process		Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Replication Chromatin Organization Nucleosome Assembly Transcription, DNA-templated Multicellular Organismal Development Cell Proliferation Gene Expression Negative Regulation Of Cell Growth CENP-A Containing Nucleosome Assembly Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Cellular Heat Acclimation
Pathways			Chromosome Maintenance HDACs deacetylate histones Chromatin organization RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Epigenetic regulation of gene expression Cellular Senescence HATs acetylate histones PRC2 methylates histones and DNA RMTs methylate histone arginines Chromatin modifying enzymes Nucleosome assembly Oxidative Stress Induced Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CHD4 HDAC1 HDAC2 MBD2 MBD3 MTA1 MTA2 POLD3 RBBP4 RBBP7	28 interactors: APPL1 APPL2 BCL11B BRCA1 BRMS1 BRMS1L CHD4 CREBBP DHX30 ESR1 GATAD2B HDAC1 HDAC2 HIST3H3 ING1 LINC00152 MBD3 MBD3L2 MTA2 NR2E3 RB1 RBBP4 RBP1 SALL2 SAP30 SIN3A SUV39H1 TWIST1
Entrez ID		125997	5931
HPRD ID		12139	04231
Ensembl ID		ENSG00000230522	ENSG00000102054
Uniprot IDs		Q8NHZ7	E9PC52 Q16576 Q6FHQ0
PDB IDs			3CFS 3CFV
Enriched GO Terms of Interacting Partners?		ATP-dependent Chromatin Remodeling Chromatin Remodeling Regulation Of Gene Expression, Epigenetic Chromosome Organization Negative Regulation Of Gene Expression, Epigenetic Chromatin Organization Chromatin Modification Organelle Organization Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Histone Deacetylation Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Deacetylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Circadian Regulation Of Gene Expression Fungiform Papilla Formation Negative Regulation Of Cellular Metabolic Process RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Fungiform Papilla Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Receptor Biosynthetic Process Gene Expression Fungiform Papilla Development Eyelid Development In Camera-type Eye Hair Follicle Placode Formation Histone Modification Tongue Morphogenesis Regulation Of Receptor Biosynthetic Process Histone H4 Deacetylation Chromatin Assembly Or Disassembly DNA Metabolic Process Circadian Rhythm	Chromatin Organization Chromatin Modification Chromosome Organization Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression, Epigenetic Transcription, DNA-templated Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Remodeling Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process ATP-dependent Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Cellular Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Histone Modification Regulation Of Gene Expression Organelle Organization Macromolecule Biosynthetic Process Histone Deacetylation Protein Deacetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Rhythmic Process Histone H3-K9 Modification Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Eyelid Development In Camera-type Eye Tissue Development Negative Regulation Of Histone Acetylation
Tagcloud ?			accessibility acetyltransferase alanine applicable bait code govern h3s10 hat1 mimic nonhydrolyzable outlined partners phosphonomethylen pma posttranslational ptms pull recruit retinoblastoma s10 scheme silac studying tail tails threonine uncovered unmodified
Tagcloud (Difference) ?			accessibility acetyltransferase alanine applicable bait code govern h3s10 hat1 mimic nonhydrolyzable outlined partners phosphonomethylen pma posttranslational ptms pull recruit retinoblastoma s10 scheme silac studying tail tails threonine uncovered unmodified
Tagcloud (Intersection) ?