MTA2 and FKBP3

Number of citations of the paper that reports this interaction (PMID 12920132)
28

Data Source:
BioGRID (pull down)

		MTA2	FKBP3
Gene Name		metastasis associated 1 family, member 2	FK506 binding protein 3, 25kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Deacetylase Complex Nuclear Chromatin Nucleoplasm Transcription Factor Complex Membrane NuRD Complex Protein Complex	Nucleus Endoplasmic Reticulum Membrane
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Binding Transcription Factor Activity RNA Polymerase II Transcription Factor Binding RNA Polymerase II Repressing Transcription Factor Binding Sequence-specific DNA Binding Transcription Factor Activity Histone Deacetylase Activity Protein Binding Zinc Ion Binding Nucleosomal DNA Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Receptor Activity Protein Binding FK506 Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Chromatin Organization Chromatin Assembly Or Disassembly Histone Deacetylation ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription From RNA Polymerase II Promoter	Protein Peptidyl-prolyl Isomerization Chaperone-mediated Protein Folding
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: APPL1 APPL2 BCL11B ESR1 FKBP3 HDAC2 HIST3H3 HNRNPD MBD3 MBD3L2 MED30 NACC2 RBBP4 RBBP7 SATB1 SATB2 SPEN TP53 TSC22D3 UBE3C YY1	13 interactors: BARD1 CALM1 CSNK2A1 CSNK2A2 CSNK2B FBXO25 HDAC1 HDAC2 MTA2 NEDD4 NEDD4L SRPK1 YY1
Entrez ID		9219	2287
HPRD ID		07233	01743
Ensembl ID		ENSG00000149480	ENSG00000100442
Uniprot IDs		O94776	Q00688
PDB IDs			1PBK 2KFV
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Chromosome Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Chromatin Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Metabolic Process Chromatin Modification Regulation Of Nitrogen Compound Metabolic Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter ATP-dependent Chromatin Remodeling Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Macromolecule Biosynthetic Process Cell Proliferation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Gene Expression, Epigenetic Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Rhythmic Process Regulation Of Apoptotic Process Forebrain Neuron Fate Commitment Cellular Metabolic Process Regulation Of Cell Death DNA Metabolic Process Negative Regulation Of Cell Proliferation Chromatin Assembly	Negative Regulation Of Cellular Metabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Cell Cycle Histone Deacetylation Regulation Of Protein Metabolic Process Protein Deacetylation Positive Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Protein Metabolic Process ATP-dependent Chromatin Remodeling Fungiform Papilla Formation Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Fungiform Papilla Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Receptor Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Fungiform Papilla Development Negative Regulation Of Sodium Ion Transport Cellular Response To Light Stimulus Cellular Metabolic Process Eyelid Development In Camera-type Eye Negative Regulation Of Ion Transport Regulation Of Gene Expression Hair Follicle Placode Formation Tongue Morphogenesis Cellular Response To Stimulus Regulation Of Receptor Biosynthetic Process Negative Regulation Of Biosynthetic Process Histone H4 Deacetylation Negative Regulation Of Transport Neuron Projection Development Cellular Response To Radiation Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cell Surface Receptor Signaling Pathway Nitrogen Compound Metabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Protein Polyubiquitination Neuron Development Anatomical Structure Morphogenesis
Tagcloud ?		ag ag1478 blocking combat combinatorial dosage egfr exerts fasn greatly hsp90 ideal iialpha iressa isotope labeling lc mechanistically oncogenes phosphatidylinositol pi3k pi4kiialpha prdx2 presents proteomic silac strengthened ultimately xenograft
Tagcloud (Difference) ?		ag ag1478 blocking combat combinatorial dosage egfr exerts fasn greatly hsp90 ideal iialpha iressa isotope labeling lc mechanistically oncogenes phosphatidylinositol pi3k pi4kiialpha prdx2 presents proteomic silac strengthened ultimately xenograft
Tagcloud (Intersection) ?